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- Table of Contents
TNFSF15 Antibodies
AND TNFSF15 ELISA kits, TNFSF15 Proteins
Many biological assays use antibodies to detect TNFSF15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFSF15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFSF15 antibodies...
Designing a Western blot for TNFSF15? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFSF15 Western Blot GuideTNFSF15 Infographic by Boster Bio
All TNFSF15 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB, ELISA (Cap)
$370
Cat # A02402-1
100 μg/vial
Cat # A02402-1
100 μg/vial
Human
ELISA
$480
Cat # EKC1658
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1658
1 kit, containing one 96-well plate and all necessary reagents
Human
Cell Culture
$77
Cat # PROTO95150-5
5ug,20ug,100ug
Cat # PROTO95150-5
5ug,20ug,100ug
SDS-PAGE, Bioactivity
$281
Cat # PROTO95150-4
Starting from 10ug
Cat # PROTO95150-4
Starting from 10ug
TNFSF15 Overview
Facts about Tumor necrosis factor ligand superfamily member 15.
Tumor necrosis factor ligand superfamily member 15 (TNFSF15)
Receptor for TNFRSF25 and TNFRSF6B.
Mediates activation of NF-kappa-B.Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFSF15 |
| Uniprot: | O95150 |
| Entrez: | 9966 |
Family
| Belongs to: |
|---|
| tumor necrosis factor family |
Alternative Names
MGC129934; MGC129935; TL1A; TL1Vascular endothelial cell growth inhibitor; TNF superfamily ligand TL1A; TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand superfamily member 15; vascular endothelial growth inhibitor-192A; VEGI; VEGI192A; VEGITNF ligand-related molecule 1
Molecular Weight
Mass (kDA):
28.087 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q32 |
| Sequence: | 9; NC_000009.12 (114784635..114806039, complement) |
Tissue Specificity
Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
Subcellular Localizations
Membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 15, secreted form]: Secreted.
Diseases
- Crohn Disease
- Inflammation
- Inflammatory Bowel Diseases
- Intestinal Diseases
- Malignant Neoplasms
- Colitis
- Ulcer
- Neoplasms
- Ulcerative Colitis
- Pathologic Neovascularization
- Tumor Angiogenesis
- Autoimmune Reaction
Interacting Proteins
- TNFRSF6B
Pathways
- Pathogenesis
- Angiogenesis
- Cell Proliferation
- Cell Growth
- Secretion
- Immune Response
- Endothelial Cell Proliferation
- Cell Differentiation
- Cytokine Production
- Cell Death
- Cell Activation
- T Cell Activation
- Aging
PTMs
- Phosphorylation
- Biotinylation
- Reduction
Research Areas
- Apoptosis
- Biologically Active Proteins
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFSF15
bosterbio.com/bosterbio-gene-info-cards/TNFSF15
References
PMID: 9872942 by Zhai Y., et al. VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo.
PMID: 11923219 by Chew L.-J., et al. A novel secreted splice variant of vascular endothelial cell growth inhibitor.