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Tropomyosin beta chain Antibodies
AND TPM2 ELISA kits, Tropomyosin beta chain Proteins
Many biological assays use antibodies to detect Tropomyosin beta chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tropomyosin beta chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tropomyosin beta chain antibodies...
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TPM2 Infographic by Boster Bio
All TPM2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$405
Cat # A03082
100ul
Cat # A03082
100ul
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # A03082-1
100 μg/vial
Cat # A03082-1
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M03082
100 μl/vial
Cat # M03082
100 μl/vial
TPM2 Overview
Facts about Tropomyosin beta chain.
Tropomyosin beta chain (TPM2)
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.
Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Gene Information
| Human | |
|---|---|
| Gene Name: | TPM2 |
| Uniprot: | P07951 |
| Entrez: | 7169 |
Family
| Belongs to: |
|---|
| tropomyosin family |
Alternative Names
distal, type 1; tropomyosin 2 (beta)
Molecular Weight
Mass (kDA):
32.851 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (35681993..35690056, complement) |
Tissue Specificity
Present in primary breast cancer tissue, absent from normal breast tissue.
Subcellular Localizations
Cytoplasm, cytoskeleton. Associates with F-actin stress fibers.
Diseases
- Myopathy
- Weakness
- Arthrogryposis
- Muscle Weakness
- Myopathies, Nemaline
- Distal Arthrogryposis Syndrome
- Congenital Myopathy (disorder)
- Muscle Contracture
- Malignant Neoplasms
- Neoplasms
- Congenital Structural Myopathy
- Congenital Abnormality
Pathways
- Muscle Contraction
- Localization
- Pathogenesis
- Cell Motility
- Transport
- Cell Migration
- Regulation Of Muscle Contraction
- Cell Proliferation
- Methylation
- Cell Adhesion
- Regulation Of Cytoskeleton
- Cytokinesis
- Reverse Transcription
PTMs
- Methylation
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TPM2
bosterbio.com/bosterbio-gene-info-cards/TPM2
References
PMID: 3865200 by MacLeod A.R., et al. A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism.
PMID: 3368322 by Widada J.S., et al. Complete nucleotide sequence of the adult skeletal isoform of human skeletal muscle beta-tropomyosin.