Thyroid peroxidase Antibodies

AND TPO ELISA kits, Thyroid peroxidase Proteins

Many biological assays use antibodies to detect Thyroid peroxidase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thyroid peroxidase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thyroid peroxidase antibodies...

We validate the specificity of these antibodies to Thyroid peroxidase by testing them on tissues known to express TPO positively and negatively. Browse below to find the TPO antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TPO Infographic by Boster Bio

All TPO Products

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Product

Figures

Specificity

Applications

Price

Anti-TPO Monoclonal Antibody

4 Q&As

Western blot analysis of TPO expression in Human thyroid lysate

IHC analysis of TPO using anti-TPO antibody (M00320)

Human

IP, IHC, WB

$370
Cat # M00320
100 μl

Anti-TPO (Thyroid Peroxidase) Rabbit Monoclonal Antibody, Clone#RM368

1 Q&As

Western Blotting resultWestern Blot of TT cell lysate using anti-TPO rabbit monoclonal antibody (Clone RM368) at a 1:200 dilution

Human

IHC, WB

$449
Cat # M00320-1
100uL

Thyroid Peroxidase (TPO) (NM_000547) Human Recombinant Protein

1 Q&As

Coomassie blue staining of purified TPO protein

$1062
Cat # PROTP07202
20 µg

Anti-Thyroid Peroxidase Rabbit Monoclonal Antibody

Human

IP, IHC, WB

$370
Cat # M00320-2
100 μl/vial

TPO Overview

Facts about Thyroid peroxidase.

TPO 3D structure. Source: alphafold

Thyroid peroxidase (TPO)

Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). .

Gene Information

Human
Gene Name:	TPO
Uniprot:	P07202
Entrez:	7173

Family

Belongs to:

peroxidase family

Alternative Names

EC 1.11.1; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; TPXEC 1.11.1.8

Molecular Weight

Mass (kDA):
102.963 kDA

Genomic Context


Human

Location:	2p25.3
Sequence:	2; NC_000002.12 (1413288..1543673)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface.

Diseases

Autoimmune Reaction
Thyroid Diseases
Hashimoto Disease
Hypothyroidism
Thyroiditis
Graves Disease
Autoimmune Diseases
Malignant Neoplasms
Leukemia
Goiter
Neoplasms
Thrombocytosis

Autoimmunity
Thyroid Neoplasm
Carcinoma
Purpura, Thrombocytopenic, Idiopathic
Hyperthyroidism
Anemia
Malignant Neoplasm Of Thyroid

Pathways

Pathogenesis
Cell Proliferation
Secretion
Localization
Cell Cycle
Cell Growth
Platelet Activation
Platelet Aggregation
Megakaryocyte Differentiation
Transport
Megakaryocyte Development
Platelet Formation
Immune Response

Cell Differentiation
Regeneration
Translation
Excretion
Cell Division
Cell Death
Coagulation

PTMs

Phosphorylation
Iodination
Oxidation
Glycosylation
Cleavage
Reduction
Biotinylation
Methylation

Demethylation
Ubiquitination
Acetylation
Deglycosylation
Deiodination
Carboxylation
Citrullination
Bromination

Nitration

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TPO

References

PMID: 3475693 by Kimura S., et al. Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs.

PMID: 3453124 by Libert F., et al. Complete nucleotide sequence of the human thyroperoxidase-microsomal antigen cDNA.