Tripeptidyl-peptidase 2 Antibodies

AND TPP2 ELISA kits, Tripeptidyl-peptidase 2 Proteins

Many biological assays use antibodies to detect Tripeptidyl-peptidase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tripeptidyl-peptidase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tripeptidyl-peptidase 2 antibodies...

We validate the specificity of these antibodies to Tripeptidyl-peptidase 2 by testing them on tissues known to express TPP2 positively and negatively. Browse below to find the TPP2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TPP2 Infographic by Boster Bio

All TPP2 Products

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Anti-Tripeptidyl-peptidase 2 TPP2 Antibody

Western blot analysis of extracts of various cell lines, using TPP2 antibody at 1:1000 dilution

Immunofluorescence analysis of U2OS cells using TPP2 antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06668-1
100ul

Tripeptidyl peptidase II (TPP2) (NM_003291) Human Over-expression Lysate

Human

$628
Cat # LS007174
20 µg, 100 µg

Anti-Tripeptidyl peptidase II/TPPII/TPP2 Antibody Picoband®

Western blot analysis of Tripeptidyl peptidase II/TPPII/TPP2 using anti-Tripeptidyl peptidase II/TPPII/TPP2 antibody (A06668-2)

IHC analysis of Tripeptidyl peptidase II/TPPII/TPP2 using anti-Tripeptidyl peptidase II/TPPII/TPP2 antibody (A06668-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06668-2
100 μg/vial

Anti-Tripeptidyl peptidase II Rabbit Monoclonal Antibody

Western blot analysis of Tripeptidyl peptidase II expression in HepG2 cell lysate

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M06668
100 µl/vial

TPP2 Overview

Facts about Tripeptidyl-peptidase 2.

TPP2 3D structure. Source: alphafold

Tripeptidyl-peptidase 2 (TPP2)

Part of the proteolytic cascade acting downstream of the 26S proteasome from the ubiquitin-proteasome pathway. Might be able to match the 26S proteasome function to some extent under conditions in which the latter is inhibited.

Stimulates adipogenesis (By similarity). .

Gene Information

Human
Gene Name:	TPP2
Uniprot:	P29144
Entrez:	7174

Family

Belongs to:

peptidase S8 family

Alternative Names

EC 3.4.14.10; FLJ40359; TPP-2; TPP-II; Tripeptidyl aminopeptidase; tripeptidyl peptidase II; tripeptidyl-peptidase 2; Tripeptidyl-peptidase II

Molecular Weight

Mass (kDA):
138.35 kDA

Genomic Context


Human

Location:	13q33.1
Sequence:	13; NC_000013.11 (102596985..102679958)

Subcellular Localizations

Cytoplasm. Nucleus. Translocates to the nucleus in responce to gamma-irradiation.

Diseases

Neoplasms
Glioblastoma Multiforme
Malignant Squamous Cell Neoplasm
Glioma
Glioblastoma
Hyperplasia
Brain Neoplasms

Carcinoma
Carcinogenesis

Interacting Proteins

EHHADH
POLB
PPP1R16A

Pathways

Localization
Transport
Dna Repair
Proteolysis
Spindle Assembly Checkpoint
Rna Processing
Rna Interference

Spindle Assembly

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TPP2

References

PMID: 1840501 by Tomkinson B.; Nucleotide sequence of cDNA covering the N-terminus of human tripeptidyl peptidase II.

PMID: 1670990 by Tomkinson B., et al. Characterization of cDNA for human tripeptidyl peptidase II: the N- terminal part of the enzyme is similar to subtilisin.