TREX2 Antibodies

AND TREX2 ELISA kits, TREX2 Proteins

Many biological assays use antibodies to detect TREX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TREX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TREX2 antibodies...

We validate the specificity of these antibodies to TREX2 by testing them on tissues known to express TREX2 positively and negatively. Browse below to find the TREX2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for TREX2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the TREX2 IHC Guide

TREX2 Infographic by Boster Bio

All TREX2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TREX2 Antibody Picoband®

Western blot analysis of TREX2 using anti-TREX2 antibody (PB10105)

Human

$370
Cat # PB10105
100 μg/vial

Anti-TREX2 Antibody

Western blot analysis of TREX2 in rat liver tissue lysate with TREX2 antibody at 2

Immunohistochemistry of TREX2 in human liver tissue with TREX2 antibody at 2

Immunofluorescence of TREX2 in Human Liver cells with TREX2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A08960
0.1 mg

TREX2 (NM_080701) Human Over-expression Lysate

Human

$628
Cat # LS011219
20 µg, 100 µg

TREX2 (NM_080701) Human Recombinant Protein

Coomassie blue staining of purified TREX2 protein

$1249
Cat # PROTQ9BQ50
20 µg

TREX2 Overview

Facts about Three prime repair exonuclease 2.

TREX2 3D structure. Source: alphafold

Three prime repair exonuclease 2 (TREX2)

Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.

Gene Information

Human
Gene Name:	TREX2
Uniprot:	Q9BQ50
Entrez:	11219

Family

Belongs to:

exonuclease superfamily

Alternative Names

3'-5' exonuclease TREX2; EC 3.1.11.2; three prime repair exonuclease 2,3'-5' exonuclease TREX2 long form

Molecular Weight

Mass (kDA):
25.922 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (153444720..153446487, complement)

Tissue Specificity

Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Carcinoma
Neoplasms
Chromosome Breakage
Lupus Erythematosus, Systemic
Retinal Diseases
Genomic Instability
Chromosomal Translocation
Hyperplasia
Dna Degradation, Necrotic
Chromosome Break
Malignant Neoplasm Of Breast

Communicable Diseases
Carcinogenesis
Chilblain Lupus Erythematosus
Sjogren's Syndrome
Mammary Neoplasms
Mammary Neoplasms, Experimental
Cell Transformation, Neoplastic

Pathways

Transport
Dna Replication
Cell Proliferation
Dna Repair
Mrna Transport
Cell Cycle
Response To Superoxide
Cornification
Metaphase
Nuclear Export
Double-strand Break Repair

Nuclear Transport
Translation
Cell Death
Mrna Processing
Rna Processing

PTMs

Cleavage

Phosphorylation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TREX2

References

PMID: 10391904 by Mazur D.J., et al. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.

PMID: 11278605 by Mazur D.J., et al. Structure and expression of the TREX1 and TREX2 3'-->5' exonuclease genes.