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TREX2 Antibodies
AND TREX2 ELISA kits, TREX2 Proteins
Many biological assays use antibodies to detect TREX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TREX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TREX2 antibodies...
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TREX2 Infographic by Boster Bio
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TREX2 Overview
Facts about Three prime repair exonuclease 2.
Three prime repair exonuclease 2 (TREX2)
Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TREX2 |
| Uniprot: | Q9BQ50 |
| Entrez: | 11219 |
Family
| Belongs to: |
|---|
| exonuclease superfamily |
Alternative Names
3'-5' exonuclease TREX2; EC 3.1.11.2; three prime repair exonuclease 2,3'-5' exonuclease TREX2 long form
Molecular Weight
Mass (kDA):
25.922 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq28 |
| Sequence: | X; NC_000023.11 (153444720..153446487, complement) |
Tissue Specificity
Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Chromosome Breakage
- Lupus Erythematosus, Systemic
- Retinal Diseases
- Genomic Instability
- Chromosomal Translocation
- Hyperplasia
- Dna Degradation, Necrotic
- Chromosome Break
- Malignant Neoplasm Of Breast
Pathways
- Transport
- Dna Replication
- Cell Proliferation
- Dna Repair
- Mrna Transport
- Cell Cycle
- Response To Superoxide
- Cornification
- Metaphase
- Nuclear Export
- Double-strand Break Repair
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TREX2
bosterbio.com/bosterbio-gene-info-cards/TREX2
References
PMID: 10391904 by Mazur D.J., et al. Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.
PMID: 11278605 by Mazur D.J., et al. Structure and expression of the TREX1 and TREX2 3'-->5' exonuclease genes.