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- Table of Contents

Facts about TLR4 interactor with leucine rich repeats.
Part of the TLR4 signaling complex.
Mediate the innate immune response to bacterial lipopolysaccharide (LPS) resulting in cytokine secretion..
| Human | |
|---|---|
| Gene Name: | TRIL |
| Uniprot: | Q7L0X0 |
| Entrez: | 9865 |

| Belongs to: |
|---|
| No superfamily |

; KIAA0644; TLR4 Interactor With Leucine Rich Repeats; TRIL
Mass (kDA):
88.723 kDA

| Human | |
|---|---|
| Location: | 7p14.3 |
| Sequence: | 7; NC_000007.14 (28953358..28958330, complement) |
Highly expressed in the brain, ovary, small intestine and spleen.
Membrane; Single-pass type I membrane protein.




PMID: 19710467 by Carpenter S., et al. TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain.
PMID: 26477546 by Srour M., et al. Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.