TRPC1 Antibodies

AND TRPC1 ELISA kits, TRPC1 Proteins

Many biological assays use antibodies to detect TRPC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRPC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRPC1 antibodies...

We validate the specificity of these antibodies to TRPC1 by testing them on tissues known to express TRPC1 positively and negatively. Browse below to find the TRPC1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for TRPC1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the TRPC1 Western Blot Guide

TRPC1 Infographic by Boster Bio

All TRPC1 Products

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Product

Figures

Specificity

Applications

Price

Anti-TRP1 / TYRP1 Reference Antibody (flanvotumab)

The purity of Anti-TRP1/TYRP1 Reference Antibody (flanvotumab)is more than 95%

Human, Mouse

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M01492-1
100 μg

TRPC1 (NM_003304) Human Over-expression Lysate

Human

$960
Cat # LS007220
20 µg, 100 µg

Anti-TRPC1 Rabbit Monoclonal Antibody

Western blot analysis of TRPC1 using anti-TRPC1 antibody (M01492)

Human, Mouse, Rat

$370
Cat # M01492
100 μl/vial

TRPC1 Overview

Facts about Short transient receptor potential channel 1.

TRPC1 3D structure. Source: alphafold

Short transient receptor potential channel 1 (TRPC1)

Thought to form a receptor-activated non-selective calcium permeant cation channel. Likely is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.

Appears to be also activated by intracellular calcium store depletion. .

Gene Information

Human
Gene Name:	TRPC1
Uniprot:	P48995
Entrez:	7220

Family

Belongs to:

transient receptor (TC 1.A.4) family

Alternative Names

HTRP-1; MGC133334; MGC133335; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; transient receptor potential channel 1; Transient receptor protein 1; TRP-1; TRP1short transient receptor potential channel 1; TrpC1

Molecular Weight

Mass (kDA):
91.212 kDA

Genomic Context


Human

Location:	3q23
Sequence:	3; NC_000003.12 (142724034..142807888)

Tissue Specificity

Seems to be ubiquitous.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Hypertensive Disease
Malignant Neoplasms
Hypertrophy
Hypoxia
Pathologic Vasoconstriction
Neoplasms
Dystrophy
Muscular Dystrophy
Pulmonary Hypertension
Cardiovascular Diseases
Muscular Dystrophy, Duchenne
Asthma
Cardiac Hypertrophy

Kidney Diseases
Atherosclerosis
Carcinoma
Nervousness
Idiopathic Pulmonary Hypertension
Diabetes Mellitus
Malignant Neoplasm Of Prostate

Interacting Proteins

CAV1
ORAI1
PKD2
STIM1
Trpv4

Pathways

Store-operated Calcium Entry
Cell Proliferation
Localization
Secretion
Cell Migration
Pathogenesis
Vasoconstriction
Cell Death
Rna Interference
Cell Cycle
Regeneration
Axon Guidance
Membrane Depolarization

Gene Silencing
Synaptic Transmission
Transport
Cell Differentiation
Cell Growth
Cellular Localization
Muscle Cell Proliferation

PTMs

Phosphorylation
Biotinylation
Cleavage
Glycosylation

Myristoylation
Nitration
Nitrosylation
Reduction

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRPC1

References

PMID: 7589464 by Zhu X., et al. Molecular cloning of a widely expressed human homologue for the Drosophila trp gene.

PMID: 7568191 by Wes P.D., et al. TRPC1, a human homolog of a Drosophila store-operated channel.