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- Table of Contents

Facts about Transient receptor potential cation channel subfamily V member 3.
Activation exhibits an outward rectification. May associate with TRPV1 and might modulate its activity.
| Human | |
|---|---|
| Gene Name: | TRPV3 |
| Uniprot: | Q8NET8 |
| Entrez: | 162514 |

| Belongs to: |
|---|
| transient receptor (TC 1.A.4) family |

transient receptor potential cation channel subfamily V member 3; transient receptor potential cation channel, subfamily V, member 3; TRPV3; vanilloid receptor 3; Vanilloid receptor-like 3; vanilloid receptor-related osmotically activated channel protein; Vanilloid R-like 3; VRL3; VRL-3
Mass (kDA):
90.636 kDA

| Human | |
|---|---|
| Location: | 17p13.2 |
| Sequence: | 17; NC_000017.11 (3510502..3557812, complement) |
Abundantly expressed in CNS. Widely expressed at low levels. Detected in dorsal root ganglion (at protein level). Expressed in the keratinocyte layers of the outer root sheath and, to lesser extent, to the matrix of the hair follicles (at protein level).
Membrane; Multi-pass membrane protein.




PMID: 12077606 by Smith G.D., et al. TRPV3 is a temperature-sensitive vanilloid receptor-like protein.
PMID: 12077604 by Xu H., et al. TRPV3 is a calcium-permeable temperature-sensitive cation channel.