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TTLL4 Antibodies

AND TTLL4 ELISA kits, TTLL4 Proteins

Many biological assays use antibodies to detect TTLL4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TTLL4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TTLL4 antibodies...

We validate the specificity of these antibodies to TTLL4 by testing them on tissues known to express TTLL4 positively and negatively. Browse below to find the TTLL4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TTLL4 Infographic by Boster Bio

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All TTLL4 Products

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TTLL4 (NM_014640) Human Over-expression Lysate

TTLL4 Human Over-expression Lysates NM_014640

TTLL4 Human Over-expression Lysates NM_014640

Human

$628
Cat # LS009654
20 µg, 100 µg

TTLL4 Overview

Facts about Tubulin polyglutamylase TTLL4.

TTLL4 3D structure

TTLL4 3D structure. Source: alphafold

Tubulin polyglutamylase TTLL4 (TTLL4)

Glutamylase that preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved from the side-chain initiation step of this polyglutamylation reaction as opposed to in the elongation step.

Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4.

Gene Information

Human
Gene Name:	TTLL4
Uniprot:	Q14679
Entrez:	9654

Gene Information

Family

Belongs to:

tubulin--tyrosine ligase family

Family

Alternative Names

EC 6.-; KIAA0173Tubulin--tyrosine ligase-like protein 4; tubulin polyglutamylase TTLL4; tubulin tyrosine ligase-like family, member 4

Molecular Weight

Mass (kDA):
133.378 kDA

Molecular Weight

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (218710835..218757484)

Subcellular Localizations

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Located in cilia. In some cells, also found in basal bodies.

Subcellular Localization

Diseases

Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Carcinoma, Pancreatic Ductal
Malignant Neoplasms
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Carcinogenesis

Ductal Breast Carcinoma

Disease

Pathways

Histone H3 Acetylation
Nucleosome Assembly
Cell Growth
Chromatin Remodeling

Pathways

PTMs

Acetylation

Glutamylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TTLL4

References

PMID: 25959773 by Garnham C.P., et al. Multivalent microtubule recognition by tubulin tyrosine ligase-like family glutamylases.