Tubulin polyglutamylase TTLL4 (TTLL4)

Glutamylase that preferentially modifies beta-tubulin and non-tubulin proteins, such as NAP1L1, NAP1L4 and CGAS. Involved from the side-chain initiation step of this polyglutamylation reaction as opposed to in the elongation step.

Involved in formation of short side-chains. Mediates initiation of polyglutamylation of nucleosome assembly proteins NAP1L1 and NAP1L4.