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- Table of Contents
TXN2 Antibodies
AND TXN2 ELISA kits, TXN2 Proteins
Many biological assays use antibodies to detect TXN2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TXN2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TXN2 antibodies...
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TXN2 Infographic by Boster Bio
All TXN2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04586
100 μl
Cat # M04586
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04586-1
100 μg/vial
Cat # A04586-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04586-1
100 μg/vial
Cat # M04586-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04586-2
100 μg/vial
Cat # M04586-2
100 μg/vial
TXN2 Overview
Facts about Thioredoxin, mitochondrial.
Thioredoxin, mitochondrial (TXN2)
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TXN2 |
| Uniprot: | Q99757 |
| Entrez: | 25828 |
Family
| Belongs to: |
|---|
| thioredoxin family |
Alternative Names
mitochondrial thioredoxin; MTRX; MT-TRX; thioredoxin 2; thioredoxin, mitochondrial; Thioredoxin2; Thioredoxin-2; Trx2; TXN2
Molecular Weight
Mass (kDA):
18.383 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q12.3 |
| Sequence: | 22; NC_000022.11 (36467036..36481672, complement) |
Tissue Specificity
Widely expressed in adult (at protein level) and fetal tissues.
Subcellular Localizations
Mitochondrion.
Diseases
- Malignant Neoplasm Of Breast
- Malignant Neoplasms
- Neoplasms
- Mammary Neoplasms
- Carcinoma
- Hypoxia
- Inflammation
- Retinal Diseases
- Brain Injuries
- Diabetes Mellitus
- Ductal Breast Carcinoma
- Carcinoma, Lobular
Interacting Proteins
- AGTRAP
- AP2B1
- CCDC114
- DCTD
- FAM9B
- GPRASP2
- KRT40
- MAPRE2
- MAPRE3
- MRFAP1L1
Pathways
- Cell Death
- Aging
- Response To Oxidative Stress
- Cell Proliferation
- Transport
- Electron Transport
- Electron Transport Chain
- Release Of Cytochrome C From Mitochondria
- Cell Growth
- Protein Phosphorylation
- Neural Tube Closure
- Gene Silencing
- Programmed Cell Death
PTMs
- Oxidation
- Reduction
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TXN2
bosterbio.com/bosterbio-gene-info-cards/TXN2
References
PMID: 12032145 by Chen Y., et al. Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells.
PMID: 12080052 by Damdimopoulos A.E., et al. Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death.