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- Table of Contents
TM4SF1 Antibodies
AND TM4SF1 ELISA kits, TM4SF1 Proteins
Many biological assays use antibodies to detect TM4SF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TM4SF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TM4SF1 antibodies...
Designing a Western blot for TM4SF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TM4SF1 Western Blot GuideDesigning an IHC experiment for TM4SF1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TM4SF1 IHC GuideTM4SF1 Infographic by Boster Bio
All TM4SF1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M10368
100 μg
Cat # M10368
100 μg
TM4SF1 Overview
Facts about Transmembrane 4 L6 family member 1.
Transmembrane 4 L6 family member 1 (TM4SF1)
Gene Information
| Human | |
|---|---|
| Gene Name: | TM4SF1 |
| Uniprot: | P30408 |
| Entrez: | 4071 |
Family
| Belongs to: |
|---|
| L6 tetraspanin family |
Alternative Names
L6; M3s1; M3S1Tumor-associated antigen L6; Membrane component chromosome 3 surface marker 1; membrane component, chromosome 3, surface marker 1; TAAL6; TAAL6H-L6; TM4SF1; transmembrane 4 L six family member 1; transmembrane 4 L6 family member 1; transmembrane 4 superfamily member 1
Molecular Weight
Mass (kDA):
21.632 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q25.1 |
| Sequence: | 3; NC_000003.12 (149369022..149377781, complement) |
Tissue Specificity
Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.
Subcellular Localizations
Membrane; Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519).
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Cell Invasion
- Lung Neoplasms
- Malignant Neoplasm Of Breast
- Neoplasm Invasiveness
- Mammary Neoplasms
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Prostatic Neoplasms
- Colorectal Neoplasms
Interacting Proteins
- SDCBP2
Pathways
- Cell Migration
- Localization
- Cell Activation
- Glycosylation
- Cell Motility
- Cell Growth
- T Cell Activation
- Endocytosis
- Regeneration
- Transport
- Cell Adhesion
- Mitosis
- Complement Activation
PTMs
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TM4SF1
bosterbio.com/bosterbio-gene-info-cards/TM4SF1
References
PMID: 1565644 by Marken J.S., et al. Cloning and expression of the tumor-associated antigen L6.
PMID: 7510285 by Marken J.S., et al. Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody.