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- Table of Contents

1 Citations 6 Q&As
Facts about Tumor necrosis factor receptor superfamily member 22.
Receptor for the cytotoxic ligand TNFSF10/TRAIL.
Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis.Protects cells from TRAIL mediated apoptosis possibly through ligand competition. Can't induce the NF-kappa-B pathway.
| Mouse | |
|---|---|
| Gene Name: | Tnfrsf22 |
| Uniprot: | Q9ER62 |
| Entrez: | 79202 |

| Belongs to: |
|---|
| No superfamily |

DcTRAIL R2; DcTRAILR2; SOBa; TNFRH2; TNFRSF22
Mass (kDA):
22.375 kDA

| Mouse | |
|---|---|
| Location: | 7 F5|7 88.27 cM |
| Sequence: | 7; |
Ubiquitous.



PMID: 11063728 by Engemann S., et al. Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting.
PMID: 12466268 by Schneider P., et al. Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor- related apoptosis-inducing ligand (TRAIL).