UBE3B Antibodies

AND UBE3B ELISA kits, UBE3B Proteins

Many biological assays use antibodies to detect UBE3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE3B antibodies...

We validate the specificity of these antibodies to UBE3B by testing them on tissues known to express UBE3B positively and negatively. Browse below to find the UBE3B antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for UBE3B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the UBE3B IHC Guide

UBE3B Infographic by Boster Bio

All UBE3B Products

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Product

Figures

Specificity

Applications

Price

Anti-Ubiquitin-protein ligase E3B UBE3B Antibody

Western blot analysis of lysates from Jurkat cells, using UBE3B Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A10679-2
100ul

Anti-Ubiquitin-protein ligase E3B UBE3B Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$335
Cat # A10679
100ul

UBE3B (NM_130466) Human Over-expression Lysate

Human

$960
Cat # LS089910
20 µg, 100 µg

Anti-Ubiquitin-protein ligase E3B UBE3B Antibody

Western blot (WB) analysis of UBE3B polyclonal antibody at 1:500 dilution
Lane1:PC12 whole cell lysate(40ug)
Lane2:CT26 whole cell lysate(40ug)
Lane3:SGC7901 whole cell lysate(40ug)
Lane4:MCF-7 whole cell lysate(40ug)
Lane5:HEK293T whole cell lysate(40ug)

Human, Mouse, Rat

$405
Cat # A10679-1
100ul

UBE3B Overview

Facts about Ubiquitin-protein ligase E3B.

UBE3B 3D structure. Source: alphafold

Ubiquitin-protein ligase E3B (UBE3B)

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. .

Gene Information

Human
Gene Name:	UBE3B
Uniprot:	Q7Z3V4
Entrez:	89910

Family

Belongs to:

No superfamily

Alternative Names

DKFZp586K2123; DKFZp686A1051; EC 6.3.2; EC 6.3.2.-; FLJ45294; MGC131858; MGC78388; ubiquitin protein ligase E3B; ubiquitin-protein ligase E3B

Molecular Weight

Mass (kDA):
123.098 kDA

Genomic Context


Human

Location:	12q24.11
Sequence:	12; NC_000012.12 (109477410..109543628)

Tissue Specificity

Widely expressed.

Diseases

Spastic Paraplegia 36, Autosomal Dominant
Deafness Congenital
Spastic Paraplegia, Hereditary
Paraplegia
Malignant Neoplasms
Presbycusis
Dysequilibrium Syndrome
Complete Hearing Loss
Allelic Imbalance
Developmental Delay (disorder)
Glioblastoma

Noise-induced Hearing Loss
Methylmalonic Acidemia
Methylmalonic Acidemia Cblb Type
Growth Retardation
Haploinsufficiency
Angelman Syndrome

Pathways

Regeneration
Sensitization
Dna Repair
Proteolysis
Localization

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE3B

References

PMID: 12837265 by Gong T.-W.L., et al. Characterization of the human UBE3B gene: structure, expression, evolution, and alternative splicing.

PMID: 23200864 by Basel-Vanagaite L., et al. Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis- ptosis-intellectual-disability syndrome.