- Table of Contents
Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
|peptidase C12 family|
|Sequence:||4; NC_000004.12 (41256928..41268455)|
Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. About 30% of total UCHL1 is associated with membranes in brain.
Reactivity: Human, Mouse, Rat
Applications: Flow Cytometry, IP, IF, IHC, ICC, WB
Reactivity: Bovine, Equine, Human, Mouse, Pig, Rat
Applications: IF, IHC, ICC, WB
*More publications can be found for each product on its corresponding product page