UGT1A5 Antibodies

AND UGT1A5 ELISA kits, UGT1A5 Proteins

Many biological assays use antibodies to detect UGT1A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT1A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT1A5 antibodies...

We validate the specificity of these antibodies to UGT1A5 by testing them on tissues known to express UGT1A5 positively and negatively. Browse below to find the UGT1A5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGT1A5 Infographic by Boster Bio

All UGT1A5 Products

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Anti-UGT1A6 Antibody Picoband®

IF analysis of UGT1A6 using anti-UGT1A6 antibody (A02239-1)

Western blot analysis of UGT1A6 using anti-UGT1A6 antibody (A02239-1)

Human

ELISA, IF, ICC, WB

$370
Cat # A02239-1
100 μg/vial

UGT1A5 Overview

Facts about UDP-glucuronosyltransferase 1-5.

UGT1A5 3D structure. Source: alphafold

UDP-glucuronosyltransferase 1-5 (UGT1A5)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity).

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Gene Information

Human
Gene Name:	UGT1A5
Uniprot:	P35504
Entrez:	54579

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

GNT1; polypeptide A5; UDP glucuronosyltransferase 1 family, polypeptide A5; UDP-glucuronosyltransferase 1-E; UDPGT 1-5; UGT1; UGT1*5; UGT1E; UGT-1E

Molecular Weight

Mass (kDA):
60.071 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (233712992..233773299)

Tissue Specificity

Isoform 1 and isoform 2 are expressed in colon and small intestine. Neither isoform is expressed in liver, kidney or esophagus.

Subcellular Localizations

Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Malignant Squamous Cell Neoplasm
Drug-induced Liver Injury
Liver Carcinoma
Steatohepatitis
Malignant Neoplasm Of Breast
Hyperbilirubinemia
Steatosis
Carcinogenesis
Carcinoma
Myopathy
Patient Dependence On

Liver Neoplasms
Dysequilibrium Syndrome
Liver Regeneration Disorder
Hepatotoxicity
Esophageal Neoplasms
Chemical Carcinogenesis

Pathways

Excretion
Conjugation
Transport
Regeneration
Reverse Transcription
Bilirubin Conjugation

Secretion

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT1A5

References

PMID: 1339448 by Ritter J.K., et al. A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

PMID: 11434514 by Gong Q.H., et al. Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.