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- Table of Contents
UL16-binding protein 1 Antibodies
AND ULBP1 ELISA kits, UL16-binding protein 1 Proteins
Many biological assays use antibodies to detect UL16-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UL16-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UL16-binding protein 1 antibodies...
Designing a Western blot for UL16-binding protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ULBP1 Western Blot GuideDesigning an IHC experiment for UL16-binding protein 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ULBP1 IHC GuideULBP1 Infographic by Boster Bio
All ULBP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04323-1
100 μg/vial
Cat # A04323-1
100 μg/vial
ULBP1 Overview
Facts about UL16-binding protein 1.
UL16-binding protein 1 (ULBP1)
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ULBP1 |
| Uniprot: | Q9BZM6 |
| Entrez: | 80329 |
Family
| Belongs to: |
|---|
| MHC class I family |
Alternative Names
ALCAN-beta; MULT-1; N2DL1; N2DL-1; NKG2D ligand 1; NKG2DL; NKG2DL1; RAET1I; RAET1Ialcan-beta; Retinoic acid early transcript 1I; UL16 binding protein 1; UL16-binding protein 1; ULBP1; ULBP-1
Molecular Weight
Mass (kDA):
27.997 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.1 |
| Sequence: | 6; NC_000006.12 (149963943..149973715) |
Tissue Specificity
Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver.
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cytomegalovirus Infections
- Carcinoma
- Leukemia
- Lymphoma
- Infective Disorder
- Melanoma
- Lung Neoplasms
- Immunologic Deficiency Syndromes
- Paroxysmal Nocturnal Hemoglobinuria
- Ovarian Neoplasm
- Adenocarcinoma
Interacting Proteins
- KLRK1
Pathways
- Immune Response
- Cell Activation
- Cytolysis
- Cell Recognition
- Secretion
- Cell Proliferation
- Chemokine Production
- Cellular Senescence
- Cytokine Secretion
- Response To Heat
- Cell Maturation
- Mrna Transcription
- Translation
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ULBP1
bosterbio.com/bosterbio-gene-info-cards/ULBP1
References
PMID: 11239445 by Cosman D., et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.
PMID: 11827464 by Radosavljevic M., et al. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.