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- Table of Contents

10 Q&As
Facts about UL16-binding protein 1.
| Human | |
|---|---|
| Gene Name: | ULBP1 |
| Uniprot: | Q9BZM6 |
| Entrez: | 80329 |

| Belongs to: |
|---|
| MHC class I family |

ALCAN-beta; MULT-1; N2DL1; N2DL-1; NKG2D ligand 1; NKG2DL; NKG2DL1; RAET1I; RAET1Ialcan-beta; Retinoic acid early transcript 1I; UL16 binding protein 1; UL16-binding protein 1; ULBP1; ULBP-1
Mass (kDA):
27.997 kDA

| Human | |
|---|---|
| Location: | 6q25.1 |
| Sequence: | 6; NC_000006.12 (149963943..149973715) |
Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver.
Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.





PMID: 11239445 by Cosman D., et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.
PMID: 11827464 by Radosavljevic M., et al. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.