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- Table of Contents
Ugt1a1 Antibodies
AND Ugt1a1 ELISA kits, Ugt1a1 Proteins
Many biological assays use antibodies to detect Ugt1a1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ugt1a1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ugt1a1 antibodies...
Designing a Western blot for Ugt1a1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the UGT1A1 Western Blot GuideUgt1a1 Infographic by Boster Bio
All Ugt1a1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01866-2
100 μg/vial
Cat # A01866-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01865-1
100 μg/vial
Cat # A01865-1
100 μg/vial
SDS-PAGE, Denatured
$250
Cat # PROTP22309
Starting from 20ug
Cat # PROTP22309
Starting from 20ug
Ugt1a1 Overview
Facts about UDP-glucuronosyltransferase 1-1.
UDP-glucuronosyltransferase 1-1 (Ugt1a1)
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Glucuronates opioids and bilirubin.
.
Gene Information
| Rat | |
|---|---|
| Gene Name: | Ugt1a1 |
| Uniprot: | Q64550 |
| Entrez: | 24861 |
Family
| Belongs to: |
|---|
| UDP-glycosyltransferase family |
Alternative Names
bilirubin UDP-glucuronosyltransferase 1-1; bilirubin UDP-glucuronosyltransferase isozyme 1; Bilirubin-specific UDPGT isozyme 1; GNT1; GNT1EC 2.4.1.17; HUG-BR1; UDP glucuronosyltransferase 1 family, polypeptide A1; UDP glycosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UDPGT 1-1; UDPGT; UG-BR1; UGT1; UGT1*1; UGT1.1; UGT1-01; UGT1A; UGT-1A; UGT1A1; UGT1AUDPGT 1-1; UGT1BILIQTL1
Molecular Weight
Mass (kDA):
59.663 kDA
Genomic Context
| Rat | |
|---|---|
| Location: | 9q35 |
| Sequence: | 9; |
Diseases
- Malignant Neoplasms
- Hyperbilirubinemia
- Gilbert Disease (disorder)
- Neoplasms
- Colorectal Cancer
- Unconjugated Hyperbilirubinemia
- Crigler-najjar Syndrome
- Icterus
- Diarrhea
- Colorectal Neoplasms
- Malignant Neoplasm Of Breast
- Hyperbilirubinemia, Neonatal
Pathways
- Conjugation
- Excretion
- Transport
- Bilirubin Conjugation
- Pathogenesis
- Sulfation
- Dna Repair
- Reverse Transcription
- Secretion
- Gallstone Formation
- Cell Cycle
- Localization
- Response To Irinotecan
PTMs
- Phosphorylation
- Hydroxylation
- Oxidation
- Acetylation
- Demethylation
- Methylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ugt1a1
bosterbio.com/bosterbio-gene-info-cards/Ugt1a1
References
PMID: 7603447 by Coffman B.L., et al. Cloning and stable expression of a cDNA encoding a rat liver UDP- glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin.
PMID: 7608130 by Emi Y., et al. Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex.