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VAMP7 Antibodies
AND VAMP7 ELISA kits, VAMP7 Proteins
Many biological assays use antibodies to detect VAMP7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VAMP7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VAMP7 antibodies...
Designing a Western blot for VAMP7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VAMP7 Western Blot GuideVAMP7 Infographic by Boster Bio
All VAMP7 Products
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VAMP7 Overview
Facts about Vesicle-associated membrane protein 7.
Vesicle-associated membrane protein 7 (VAMP7)
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.
Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.
Gene Information
| Human | |
|---|---|
| Gene Name: | VAMP7 |
| Uniprot: | P51809 |
| Entrez: | 6845 |
Family
| Belongs to: |
|---|
| synaptobrevin family |
Alternative Names
FLJ54296; SYBL1; SYBL1FLJ53762; synaptobrevin-like 1; Synaptobrevin-like protein 1; tetanus neurotoxin-insensitive VAMP; Tetanus-insensitive VAMP; TIVAMP; TI-VAMP; VAMP7; VAMP-7; VAMP-7FLJ53045; vesicle-associated membrane protein 7
Molecular Weight
Mass (kDA):
24.935 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq28 and Yq12 |
| Sequence: | X|Y; NC_000023.11 (155881318..155943769) |
Tissue Specificity
Detected in all tissues tested.
Subcellular Localizations
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. In immature neurons expression is localized in vesicular structures in axons and dendrites while in mature neurons it is lo
Diseases
- Tetanus
- Neoplasms
- Malignant Neoplasms
- Immunologic Deficiency Syndromes
- Hiv Infections
- Mood Disorders
- Nervousness
- Bipolar Disorder
- Cell Invasion
- Klinefelter Syndrome
- Sclerosis
- Neoplasm Metastasis
- Dyslipidemias
Interacting Proteins
- AGFG1
- SNAP47
Pathways
- Transport
- Exocytosis
- Membrane Fusion
- Localization
- Secretion
- Endocytosis
- Secretory Pathway
- Methylation
- Phagocytosis
- Vesicle Fusion
- Dna Methylation
- Gene Silencing
- Autophagy
PTMs
- Methylation
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAMP7
bosterbio.com/bosterbio-gene-info-cards/VAMP7
References
PMID: 8640232 by D'Esposito M., et al. A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation.
PMID: 10655549 by Ciccodicola A., et al. Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.