WDHD1 Antibodies

AND WDHD1 ELISA kits, WDHD1 Proteins

Many biological assays use antibodies to detect WDHD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WDHD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WDHD1 antibodies...

We validate the specificity of these antibodies to WDHD1 by testing them on tissues known to express WDHD1 positively and negatively. Browse below to find the WDHD1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for WDHD1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the WDHD1 IHC Guide

WDHD1 Infographic by Boster Bio

All WDHD1 Products

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Product

Figures

Specificity

Applications

Price

Anti-WDHD1 Antibody

Western blot analysis of lysates from Jurkat and HepG2 cells, using WDHD1 Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse

ELISA, IF, IHC, WB

$399
Cat # A06240
100μl

Anti-WDHD1 (Q756) Antibody

Human

IHC, WB

$405
Cat # A06240-1
100ul

WDHD1 (NM_007086) Human Recombinant Protein

Coomassie blue staining of purified WDHD1 protein

$1062
Cat # PROTO75717
20 µg

WDHD1 Overview

Facts about WD repeat and HMG-box DNA-binding protein 1.

WDHD1 3D structure. Source: alphafold

WD repeat and HMG-box DNA-binding protein 1 (WDHD1)

Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complicated so as to initiate DNA replication. .

Gene Information

Human
Gene Name:	WDHD1
Uniprot:	O75717
Entrez:	11169

Family

Belongs to:

No superfamily

Alternative Names

Acidic nucleoplasmic DNA-binding protein 1; AND1; AND-1; CHTF4; CTF4; CTF4, chromosome transmission fidelity factor 4 homolog; WD repeat and HMG-box DNA binding protein 1; WD repeat and HMG-box DNA-binding protein 1

Molecular Weight

Mass (kDA):
125.967 kDA

Genomic Context


Human

Location:	14q22.2-q22.3
Sequence:	14; NC_000014.9 (54938949..55027106, complement)

Subcellular Localizations

Nucleus, nucleoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Lung Neoplasms
Non-small Cell Lung Carcinoma
Multiple Malignancy
Ataxia
Malignant Neoplasm Of Esophagus
Malignant Neoplasm Of Lung

Carcinoma
Carcinogenesis
Squamous Cell Carcinoma Of Esophagus
Esophageal Neoplasms

Interacting Proteins

KAT2A

Pathways

Dna Replication
S Phase
Cell Cycle
Sister Chromatid Cohesion
G2 Phase
Mitosis
Establishment Of Sister Chromatid Cohesion
Localization
Chromosome Segregation
Cell Cycle Arrest

Histone H3 Acetylation
Cell Death
Cell Growth
Pathogenesis

PTMs

Phosphorylation
Acetylation

Methylation
Ubiquitination

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WDHD1

References

PMID: 17761813 by Zhu W., et al. Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication.

PMID: 19805216 by Im J.S., et al. Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins.