XPA Antibodies

AND XPA ELISA kits, XPA Proteins

Many biological assays use antibodies to detect XPA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with XPA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop XPA antibodies...

We validate the specificity of these antibodies to XPA by testing them on tissues known to express XPA positively and negatively. Browse below to find the XPA antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XPA Infographic by Boster Bio

All XPA Products

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Anti-XPA Antibody

7 Q&As

Western Blot analysis of various cells using XPA Polyclonal Antibody diluted at 1:500

Western blot analysis of lysates from COLO205 cells, using XPA Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XPA Antibody

Human, Mouse

ELISA, IF, IHC, WB

$399
Cat # A01182-1
100μl

XPA Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from COLO205 cells

Human, Mouse

ELISA

$480
Cat # EKC1602
1 kit, containing one 96-well plate and all necessary reagents

Anti-XPA (H244) Antibody

Immunohistochemistry (IHC) analyzes of XPA (H244) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50

Human, Mouse, Rat

IHC

$405
Cat # A01182-3
100ul

XPA (NM_000380) Human Recombinant Protein

Coomassie blue staining of purified XPA protein

$1249
Cat # PROTP23025
20 µg

Anti-XPA Antibody Picoband®

Western blot analysis of XPA using anti-XPA antibody (A01182-4)

IF analysis of XPA using anti-XPA antibody (A01182-4) and anti-Beta Tubulin antibody (M01857-3)

Flow Cytometry analysis of 293T cells using anti-XPA antibody (A01182-4)

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A01182-4
100 µg/vial

XPA Overview

Facts about DNA repair protein complementing XP-A cells.

XPA 3D structure. Source: alphafold

DNA repair protein complementing XP-A cells (XPA)

Involved in DNA excision repair. Initiates repair by binding to damaged sites with many affinities, based on the photoproduct and the transcriptional state of the area.

Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. .

Gene Information

Human
Gene Name:	XPA
Uniprot:	P23025
Entrez:	7507

Family

Belongs to:

XPA family

Alternative Names

DNA repair protein complementing XP-A cells; excision repair-controlling; Xeroderma pigmentosum group A-complementing protein; xeroderma pigmentosum, complementation group A; XP1; XPA; XPACXP1

Molecular Weight

Mass (kDA):
31.368 kDA

Genomic Context


Human

Location:	9q22.33
Sequence:	9; NC_000009.12 (97654398..97697409, complement)

Tissue Specificity

Expressed in various cell lines and in skin fibroblasts.

Subcellular Localizations

Nucleus.

Diseases

Xeroderma Pigmentosum
Xeroderma
Malignant Neoplasms
Xeroderma Pigmentosum Complementation Group A
Neoplasms
Malignant Neoplasm Of Skin
Skin Neoplasms
Carcinoma
Carcinogenesis
Cockayne Syndrome
Malignant Neoplasm Of Lung
Malignant Squamous Cell Neoplasm

Lung Neoplasms
Neoplasms, Radiation-induced
Cell Transformation, Neoplastic
Hereditary Diseases
Decreased Immunologic Activity [pe]
Genomic Instability
Adenocarcinoma

Interacting Proteins

ERCC1
HERC2
NDEL1
RPA2
SIRT1

TRIM27
XAB2

Pathways

Dna Repair
Cell Cycle
Dna Replication
Hypersensitivity
Localization
Mismatch Repair
Aging
Cell Death
Dna Excision
S Phase
Cell Cycle Arrest
Nucleotide-excision Repair
Response To Uv

Pathogenesis
Methylation
Rna Interference
Drug Resistance
Translation
Translesion Synthesis
Cell Cycle Checkpoint

PTMs

Phosphorylation
Methylation
Cleavage
Acetylation
Oxidation
Dephosphorylation
Demethylation
Ubiquitination

Reduction
Deacetylation
Sumoylation
Nitrosylation
Deamination
Ribosylation
Nitration
Glycosylation

Research Areas

DNA Repair
Nucleotide Excision Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XPA

References

PMID: 2234061 by Tanaka K., et al. Analysis of a human DNA excision repair gene involved in group A Xeroderma pigmentosum and containing a zinc-finger domain.

PMID: 8294029 by Satokata I., et al. Genomic characterization of the human DNA excision repair-controlling gene XPAC.