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- Table of Contents
YTHDF1 Antibodies
AND YTHDF1 ELISA kits, YTHDF1 Proteins
Many biological assays use antibodies to detect YTHDF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with YTHDF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop YTHDF1 antibodies...
Designing a Western blot for YTHDF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the YTHDF1 Western Blot GuideYTHDF1 Infographic by Boster Bio
All YTHDF1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A09853-2
100 μg/vial
Cat # A09853-2
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M09853-1
20μL, 40μL, 100μL, 200μL
Cat # M09853-1
20μL, 40μL, 100μL, 200μL
YTHDF1 Overview
Facts about YTH domain-containing family protein 1.
YTH domain-containing family protein 1 (YTHDF1)
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and a few non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and equilibrium (PubMed:24284625).
Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A- containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440). .
Gene Information
| Human | |
|---|---|
| Gene Name: | YTHDF1 |
| Uniprot: | Q9BYJ9 |
| Entrez: | 54915 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C20orf21; DACA-1; Dermatomyositis associated with cancer putative autoantigen 1; FLJ20391; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1
Molecular Weight
Mass (kDA):
60.874 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q13.33 |
| Sequence: | 20; NC_000020.11 (63195429..63216131, complement) |
Subcellular Localizations
Cytoplasm.
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YTHDF1
bosterbio.com/bosterbio-gene-info-cards/YTHDF1
References
PMID: 24284625 by Wang X., et al. N-methyladenosine-dependent regulation of messenger RNA stability.
PMID: 26046440 by Wang X., et al. N(6)-methyladenosine modulates messenger RNA translation efficiency.