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- Table of Contents
14-3-3 protein epsilon Antibodies
AND YWHAE ELISA kits, 14-3-3 protein epsilon Proteins
Many biological assays use antibodies to detect 14-3-3 protein epsilon, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with 14-3-3 protein epsilon in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop 14-3-3 protein epsilon antibodies...
Designing a Western blot for 14-3-3 protein epsilon? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the YWHAE Western Blot GuideYWHAE Infographic by Boster Bio
All YWHAE Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01687-2
100 μg/vial
Cat # M01687-2
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A01687-5
100 μg/vial
Cat # A01687-5
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01687-4
100 μg/vial
Cat # A01687-4
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01687
100 μl
Cat # M01687
100 μl
Human, Mouse, Rat
ELISA
$540
Cat # EKC2638
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2638
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2552
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2552
1 kit, containing two 96-well plates and all necessary reagents
Human
$628
Cat # LS007531
20 µg, 100 µg
Cat # LS007531
20 µg, 100 µg
YWHAE Overview
Facts about 14-3-3 protein epsilon.
14-3-3 protein epsilon (YWHAE)
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a lot of partners, usually by recognition of a phosphoserine or phosphothreonine motif.
Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm (PubMed:12917326).
Gene Information
| Human | |
|---|---|
| Gene Name: | YWHAE |
| Uniprot: | P62258 |
| Entrez: | 7531 |
Family
| Belongs to: |
|---|
| 14-3-3 family |
Alternative Names
1433 epsilon; 14-3-3 epsilon; 14-3-3 protein epsilon; FLJ45465; FLJ53559,14-3-3E; KCIP-1; MDCR; MDS; mitochondrial import stimulation factor L subunit; protein kinase C inhibitor protein-1; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilonpolypeptide; YWHAE
Molecular Weight
Mass (kDA):
29.174 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.3 |
| Sequence: | 17; NC_000017.11 (1344275..1400262, complement) |
Subcellular Localizations
Nucleus. Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Miller Dieker Syndrome
- Lissencephaly
- Malignant Neoplasms
- Neoplasms
- Developmental Delay (disorder)
- Classical Lissencephalies And Subcortical Band Heterotopias
- Autistic Disorder
- Growth Retardation
- Haploinsufficiency
- Lissencephaly I
- Schizophrenia
- Epilepsy
Interacting Proteins
- ACD
- APAF1
- ARAF
- CBY1
- CDK14
- DISC1
- DLD
- DLST
- FBXO4
- HDAC4
Pathways
- Cell Cycle
- Localization
- Brain Development
- Cell Proliferation
- Cell Adhesion
- Transport
- Cell Migration
- Neurogenesis
- Cytoskeleton Organization
- Cell Growth
- Pathogenesis
- Stem Cell Differentiation
- Aging
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
Research Areas
- Cancer
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YWHAE
bosterbio.com/bosterbio-gene-info-cards/YWHAE
References
PMID: 7644510 by Conklin D.S., et al. 14-3-3 proteins associate with cdc25 phosphatases.
PMID: 8858348 by Chong S.S., et al. 14-3-3 epsilon has no homology to LIS1 and lies telomeric to it on chromosome 17p13.3 outside the Miller-Dieker syndrome chromosome region.