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14-3-3 protein eta Antibodies
AND YWHAH ELISA kits, 14-3-3 protein eta Proteins
Many biological assays use antibodies to detect 14-3-3 protein eta, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with 14-3-3 protein eta in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop 14-3-3 protein eta antibodies...
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YWHAH Infographic by Boster Bio
All YWHAH Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04219-2
100 μg/vial
Cat # A04219-2
100 μg/vial
YWHAH Overview
Facts about 14-3-3 protein eta.
14-3-3 protein eta (YWHAH)
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.
Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Gene Information
| Human | |
|---|---|
| Gene Name: | YWHAH |
| Uniprot: | Q04917 |
| Entrez: | 7533 |
Family
| Belongs to: |
|---|
| 14-3-3 family |
Alternative Names
1433 eta; 14-3-3 eta; 14-3-3 protein eta; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, etapolypeptide; YWHA1; YWHA114-3-3 eta; YWHAH
Molecular Weight
Mass (kDA):
28.219 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q12.3 |
| Sequence: | 22; NC_000022.11 (31944535..31957603) |
Tissue Specificity
Expressed mainly in the brain and present in other tissues albeit at lower levels.
Diseases
- Neoplasms
- Schizophrenia
- Carcinoma
- Malignant Neoplasms
- Bipolar Disorder
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Sarcoma
- Mammary Neoplasms
- Mental Disorders
- Neurodegenerative Disorders
- Parkinson Disease
Interacting Proteins
- AKT1S1
- BAD
- CAMKK1
- CBL
- CDC25B
- CDK14
- GREM1
- HDAC4
- LRRK2
- MAP3K3
Pathways
- Pathogenesis
- Cell Proliferation
- Localization
- Cell Cycle
- Cell Death
- S Phase
- Cell Growth
- Cell Adhesion
- Protein Phosphorylation
- Transport
- Stem Cell Differentiation
- Reproductive Process
- Mitochondrial Translocation
PTMs
- Phosphorylation
Research Areas
- Apoptosis
- Cancer
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YWHAH
bosterbio.com/bosterbio-gene-info-cards/YWHAH
References
PMID: 8218406 by Swanson K.D., et al. The human and bovine 14-3-3 eta protein mRNAs are highly conserved in both their translated and untranslated regions.
PMID: 1578511 by Ichimura-Ohshima Y., et al. cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain.