14-3-3 protein eta Antibodies

14-3-3 protein eta (YWHAH)

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.

Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Gene Information

Human
Gene Name:	YWHAH
Uniprot:	Q04917
Entrez:	7533

Family

Belongs to:
14-3-3 family

Alternative Names

1433 eta; 14-3-3 eta; 14-3-3 protein eta; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, etapolypeptide; YWHA1; YWHA114-3-3 eta; YWHAH

Molecular Weight

Mass (kDA):
28.219 kDA

Genomic Context

Human
Location:	22q12.3
Sequence:	22; NC_000022.11 (31944535..31957603)

Tissue Specificity

Expressed mainly in the brain and present in other tissues albeit at lower levels.

Diseases

• Neoplasms
• Schizophrenia
• Carcinoma
• Malignant Neoplasms
• Bipolar Disorder
• Neoplasm Metastasis
• Neoplasm Invasiveness
• Sarcoma
• Mammary Neoplasms
• Mental Disorders
• Neurodegenerative Disorders
• Parkinson Disease

• Creutzfeldt-jakob Disease
• Cell Transformation, Neoplastic
• Prion Diseases
• Metastatic Malignant Neoplasm To The Lymph Node
• Malignant Neoplasm Of Breast
• Dementia
• Anaplastic Astrocytoma

Interacting Proteins

• AKT1S1
• BAD
• CAMKK1
• CBL
• CDC25B

• CDK14
• GREM1
• HDAC4
• LRRK2
• MAP3K3

• MAP3K5
• MARK2
• MARK3
• MARK4
• PARD3

• PARD6A
• PARD6B
• PARD6G
• PRKCI
• PRKD2

• RAF1
• Rnd3
• YWHAE

Pathways

• Pathogenesis
• Cell Proliferation
• Localization
• Cell Cycle
• Cell Death
• S Phase
• Cell Growth
• Cell Adhesion
• Protein Phosphorylation
• Transport
• Stem Cell Differentiation
• Reproductive Process
• Mitochondrial Translocation

• System Development
• Translation
• Cell Differentiation
• Nuclear Import
• Oncogenesis
• Leaf Development
• Dna Repair

PTMs

• Phosphorylation

• Dephosphorylation

• Ubiquitination

Research Areas

• Apoptosis
• Cancer
• Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YWHAH

Boster Bio - The Best Uses Of The YWHAH Marker

You have probably heard about the YWHAH Marker before, but have you ever wondered how it works? This article will provide information on how this device works and the best uses. Here are some useful information for both new and seasoned Bosters. There are many uses for the YWHAH Marker, including the ones listed below.

YWHAH Marker

The YWHAH gene, which encodes a protein known as 14-3-3eta, is commonly expressed in cancer cells. This gene is highly preserved, and variants are classified according the position in exons 2. and 3. The protein contains a conserved amino acid at position 236. Nonconserved substitutions are highlighted by black boxes. There are many uses to the YWHAH genome.

YWHAH

The YWHAH Marker, a noncoding RNA, regulates osteogenic differentiation. Boster Bio has developed antibodies that are anti-14-3-3 protein beta/alpha. These antibodies react with a wide array of animal samples, and they are monoclonal as well as polyclonal. These antibodies can also affect the activity of their binding companion.