Zinc finger protein 703 Antibodies

AND ZNF703 ELISA kits, Zinc finger protein 703 Proteins

Many biological assays use antibodies to detect Zinc finger protein 703, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 703 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 703 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 703 by testing them on tissues known to express ZNF703 positively and negatively. Browse below to find the ZNF703 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Zinc finger protein 703? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ZNF703 IHC Guide

ZNF703 Infographic by Boster Bio

All ZNF703 Products

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Applications

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Anti-Zinc finger protein 703 ZNF703 Antibody

Western blot analysis of extracts of MCF7 cells, using ZNF703 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded rat pancreas using ZNF703 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded human breast cancer using ZNF703 antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A06570
100ul

ZNF703 (NM_025069) Human Over-expression Lysate

Human

$628
Cat # LS080139
20 µg, 100 µg

ZNF703 Overview

Facts about Zinc finger protein 703.

ZNF703 3D structure. Source: alphafold

Zinc finger protein 703 (ZNF703)

Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation.

May be required for segmental gene expression during hindbrain development. .

Gene Information

Human
Gene Name:	ZNF703
Uniprot:	Q9H7S9
Entrez:	80139

Family

Belongs to:

Elbow/Noc family

Alternative Names

FLJ14299; ZEPPO1; Zinc finger elbow-related proline domain protein 1; zinc finger protein 703; ZNF503L; ZPO1

Molecular Weight

Mass (kDA):
58.222 kDA

Genomic Context


Human

Location:	8p11.23
Sequence:	8; NC_000008.11 (37695782..37700019)

Tissue Specificity

Expressed in mammary epithelium.

Subcellular Localizations

Nucleus. Cytoplasm.

Diseases

Malignant Neoplasms
Mammary Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Cell Transformation, Neoplastic
Neoplasm Metastasis
Tissue Adhesions
Carcinoma
Bladder Neoplasm
Carcinoma, Transitional Cell
Adenocarcinoma
Metastatic Malignant Neoplasm To The Lung

Colonic Neoplasms
Malignant Tumor Of Colon
Neoplasm Invasiveness
Unbalanced Translocation
Neoplasms, Hormone-dependent
Pancreatic Neoplasm
Chromosomal Translocation

Pathways

Cell Adhesion
Localization
Oncogenesis
Histone Deacetylation
Cell Proliferation
Cell-cell Adhesion

PTMs

Acetylation

Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF703

References

PMID: 21328542 by Sircoulomb F., et al. ZNF703 gene amplification at 8p12 specifies luminal B breast cancer.

PMID: 21337521 by Holland D.G., et al. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.