E3 ubiquitin-protein ligase ZNRF2 (ZNRF2)

May play a role in the establishment and maintenance of neuronal transmission and plasticity through its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

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