ZNRF2 Antibodies

AND ZNRF2 ELISA kits, ZNRF2 Proteins

Many biological assays use antibodies to detect ZNRF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZNRF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZNRF2 antibodies...

We validate the specificity of these antibodies to ZNRF2 by testing them on tissues known to express ZNRF2 positively and negatively. Browse below to find the ZNRF2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNRF2 Infographic by Boster Bio

All ZNRF2 Products

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Specificity

Applications

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Anti-ZNRF2 Antibody

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung

Immunofluorescence analysis of A549 cells, using ZNRF2 Antibody

Human, Mouse

ELISA, IF, IHC, ICC

$335
Cat # A11505
100ul

Anti-ZNRF2 Rabbit Monoclonal Antibody

6 Q&As

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Western blot analysis of ZNRF2 expression in HeLa cell lysate

Human, Mouse, Rat

IHC, WB

$370
Cat # M11505
100 μl

Anti-ZNRF2 Antibody

Western blot (WB) analysis of TRAPPC6A polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate(40ug)
Lane2:H9C2 whole cell lysate(40ug)
Lane3:RAW264

Human, Mouse, Rat

$405
Cat # A11505-1
100ul

Anti-ZNRF2 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A11505-2
100ul

ZNRF2 (NM_147128) Human Over-expression Lysate

Human

$628
Cat # LS223082
20 µg, 100 µg

Anti-ZNRF2 Antibody (Monoclonal, 35Z27)

Human, Mouse, Rat

IHC, WB

$370
Cat # M11505-2
100 μl/vial

ZNRF2 Overview

Facts about E3 ubiquitin-protein ligase ZNRF2.

ZNRF2 3D structure. Source: alphafold

E3 ubiquitin-protein ligase ZNRF2 (ZNRF2)

May play a role in the establishment and maintenance of neuronal transmission and plasticity through its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Gene Information

Human
Gene Name:	ZNRF2
Uniprot:	Q8NHG8
Entrez:	223082

Family

Belongs to:

No superfamily

Alternative Names

EC 6.3.2.-; Protein Ells2; RING finger protein 202; RNF202E3 ubiquitin-protein ligase ZNRF2; zinc and ring finger 2; zinc finger/RING finger 2; Zinc/RING finger protein 2

Molecular Weight

Mass (kDA):
24.115 kDA

Genomic Context


Human

Location:	7p14.3
Sequence:	7; NC_000007.14 (30284597..30367689)

Tissue Specificity

Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.

Subcellular Localizations

Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein.

Diseases

Nervousness
Liver Carcinoma
Liver Neoplasms

Pathways

Exocytosis
Protein Ubiquitination

PTMs

Phosphorylation

Myristoylation

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNRF2

References

PMID: 14561866 by Araki T., et al. ZNRF proteins constitute a family of presynaptic E3 ubiquitin ligases.

PMID: 16215985 by Plans V., et al. The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation.

2 Publications of Boster ZNRF2 Antibodies & ELISA Kits

PubMed ID: 31026730, Xin X,Yao D,Zhang K,Han S,Liu D,Wang H,Liu X,Li G,Huang J,Wang J.Protective effe...
PubMed ID: -, Qi Xiong,Xiang Tian,Weiling Li,Lin Chen,Mei Zhou,Congyue Xu,Qin Ru Sulforaphane...

*More publications can be found for each product on its corresponding product page