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- Table of Contents
ZNRF2 Antibodies
AND ZNRF2 ELISA kits, ZNRF2 Proteins
Many biological assays use antibodies to detect ZNRF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZNRF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZNRF2 antibodies...
Designing an IHC experiment for ZNRF2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ZNRF2 IHC GuideZNRF2 Infographic by Boster Bio
All ZNRF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M11728
100 μl/vial
Cat # M11728
100 μl/vial
ZNRF2 Overview
Facts about E3 ubiquitin-protein ligase ZNRF2.
E3 ubiquitin-protein ligase ZNRF2 (ZNRF2)
May play a role in the establishment and maintenance of neuronal transmission and plasticity through its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
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Gene Information
| Human | |
|---|---|
| Gene Name: | ZNRF2 |
| Uniprot: | Q8NHG8 |
| Entrez: | 223082 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
EC 6.3.2.-; Protein Ells2; RING finger protein 202; RNF202E3 ubiquitin-protein ligase ZNRF2; zinc and ring finger 2; zinc finger/RING finger 2; Zinc/RING finger protein 2
Molecular Weight
Mass (kDA):
24.115 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7p14.3 |
| Sequence: | 7; NC_000007.14 (30284597..30367689) |
Tissue Specificity
Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.
Subcellular Localizations
Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein.
Diseases
- Nervousness
- Liver Carcinoma
- Liver Neoplasms
Pathways
- Exocytosis
- Protein Ubiquitination
PTMs
- Phosphorylation
Research Areas
- Zinc Finger
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNRF2
bosterbio.com/bosterbio-gene-info-cards/ZNRF2
References
PMID: 14561866 by Araki T., et al. ZNRF proteins constitute a family of presynaptic E3 ubiquitin ligases.
PMID: 16215985 by Plans V., et al. The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation.
2 Publications of Boster ZNRF2 Antibodies & ELISA Kits
- PubMed ID: 31026730, Xin X,Yao D,Zhang K,Han S,Liu D,Wang H,Liu X,Li G,Huang J,Wang J.Protective effe...
- PubMed ID: -, Qi Xiong,Xiang Tian,Weiling Li,Lin Chen,Mei Zhou,Congyue Xu,Qin Ru Sulforaphane...
*More publications can be found for each product on its corresponding product page