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Product Info Summary
| SKU: | A07945-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-3'-5' exoribonuclease 1 ERI1 Antibody
SKU/Catalog Number
A07945-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-3'-5' exoribonuclease 1 ERI1 Antibody catalog # A07945-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-3'-5' exoribonuclease 1 ERI1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07945-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ERI1
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07945-1 is reactive to Eri1 in Human, Mouse, Rat
Applications
A07945-1 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
39.493kDa
Background of HEXO
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Dominski Z., Mol. Cell 12:295-305(2003).
Ota T., Nat. Genet. 36:40-45(2004).
Bechtel S., BMC Genomics 8:399-399(2007)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:5000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For Eri1 (Source: Uniprot.org, NCBI)
Gene Name
Eri1
Full Name
3'-5' exoribonuclease 1
Weight
39.493kDa
Alternative Names
3' exoribonuclease; 3'-5' exonuclease ERI1; 3'EXO; 3'HEXO; EC 3.1; enhanced RNAi three prime mRNA exonuclease homolog 1; Eri-1 homolog; exoribonuclease 1; HEXO; histone mRNA 3' end-specific exonuclease; Histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; MGC35395; Protein 3'hExo; THEX1; three prime histone mRNA exonuclease 1,3'-5' exoribonuclease 1; three prime mRNA exonuclease 1 Eri1|3hexo, 3110010F15Rik, Er, Thex1, eri-1|exoribonuclease 1|3-5 exoribonuclease 1|3-5 exonuclease ERI1|enhanced RNAi protein 1|eri-1 homolog|histone mRNA 3 end-specific exonuclease|histone mRNA 3-exonuclease 1|three prime histone mRNA exonuclease 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Eri1, check out the Eri1 Infographic
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In this infographic, you will see the following information for Eri1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-3'-5' exoribonuclease 1 ERI1 Antibody (A07945-1)
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No publications found for A07945-1
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