Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody Picoband™

Acetyl Coenzyme A Carboxylase Beta antibody

Boster Bio Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody Picoband™ catalog # A03668-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A03668-2
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IHC, WB

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Product Name

Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody Picoband™

View all Acetyl Coenzyme A Carboxylase Beta Antibodies

SKU/Catalog Number

A03668-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody Picoband™ catalog # A03668-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03668-2)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Acetyl Coenzyme A Carboxylase/ACACB, which shares 64.7% amino acid (aa) sequence identity with mouse Acetyl Coenzyme A Carboxylase/ACACB.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03668-2 is reactive to ACACB in Human, Mouse, Rat

Applications

A03668-2 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee

Observed Molecular Weight

277 kDa

Calculated molecular weight

276.541kDa

Background of Acetyl Coenzyme A Carboxylase Beta

Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene. It is mapped to 12q24.11. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat
Flow Cytometry, 1-3μg/1x106 cells, Human

Validation Images & Assay Conditions

Gene/Protein Information For ACACB (Source: Uniprot.org, NCBI)

Gene Name

ACACB

Full Name

Acetyl-CoA carboxylase 2

Weight

276.541kDa

Alternative Names

ACC2ACC-beta; ACCBacetyl-CoA carboxylase 2; acetyl-CoA carboxylase beta; acetyl-Coenzyme A carboxylase beta; EC 6.4.1.2; HACC275 ACACB ACC-beta, ACC2, ACCB, HACC275 acetyl-CoA carboxylase beta acetyl-CoA carboxylase 2|acetyl-Coenzyme A carboxylase beta

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ACACB, check out the ACACB Infographic

ACACB infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ACACB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-Acetyl Coenzyme A Carboxylase/ACACB Antibody Picoband™

Question

We are currently using anti-Acetyl Coenzyme A Carboxylase/ACACB antibody A03668-2 for human tissue, and we are well pleased with the Flow Cytometry results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on canine tissues as well?

J. Anderson

Verified customer

Asked: 2016-02-15

Answer

The anti-Acetyl Coenzyme A Carboxylase/ACACB antibody (A03668-2) has not been tested for cross reactivity specifically with canine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in canine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2016-02-15

Size

Conjugation

Total: $370

SKU:A03668-2

In stock, 1 left.

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A03668-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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