Anti-AGTRAP Antibody

Product Name

Anti-AGTRAP Antibody

View all Agtrap Antibodies

SKU/Catalog Number

A04415

Size

100ul

Form

Liquid

Description

Boster Bio Anti-AGTRAP Antibody catalog # A04415. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-AGTRAP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04415)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human MLK3 around the phosphorylation site of S674.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04415 is reactive to Agtrap in Human, Mouse, Rat

Applications

A04415 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

17.525kDa

Background of Agtrap

Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.

Kikuno R., DNA Res. 6:197-205(1999).
Bechtel S., BMC Genomics 8:399-399(2007).
Heilig R., Nature 421:601-607(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-AGTRAP Antibody A04415

Western blot analysis of extracts of various cell lines

Gene/Protein Information For Agtrap (Source: Uniprot.org, NCBI)

Alternative Names

angiotensin II receptor-associated protein; AT1 receptor-associated protein; ATI receptor-associated protein; MGC29646; type I receptor-associated protein; type-1 angiotensin II receptor-associated protein Agtrap|3300002E14Rik, A, AT1R, Atrap, D4Wsu124, D4Wsu124e|angiotensin II, type I receptor-associated protein|type-1 angiotensin II receptor-associated protein|AT1 receptor-associated protein

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In this infographic, you will see the following information for Agtrap: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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