Anti-AIM2 (A78) Antibody

Product Name

Anti-AIM2 (A78) Antibody

View all AIM2 Antibodies

SKU/Catalog Number

A00443

Size

100ul

Form

Liquid

Description

Boster Bio Anti-AIM2 (A78) Antibody catalog # A00443. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-AIM2 (A78) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00443)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide, corresponding to amino acids 246-297 of Human RUNX-2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00443 is reactive to AIM2 in Human, Mouse, Rat

Applications

A00443 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

38.954kDa

Background of AIM2

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP)  is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules.  FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For AIM2 (Source: Uniprot.org, NCBI)

Alternative Names

absent in melanoma 2PYHIN4; AIM2; Gm1313; Ifi210; interferon-inducible protein AIM2; PYHIN4 AIM2 PYHIN4 absent in melanoma 2 interferon-inducible protein AIM2

For more info on AIM2, check out the AIM2 Infographic

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In this infographic, you will see the following information for AIM2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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