Product Info Summary
SKU: | A02525 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-ALAS2 Antibody
SKU/Catalog Number
A02525
Size
100ul
Form
Liquid
Description
Boster Bio Anti-ALAS2 Antibody catalog # A02525. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ALAS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02525)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SPAK around the phosphorylation site of S325.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02525 is reactive to ALAS2 in Human, Mouse, Rat
Applications
A02525 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
64.633kDa
Background of ALAS2
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Patrick Most, J. Biol. Chem., Nov 2003; 278: 48404 - 48412.
Miki Okada, J. Biol. Chem., Feb 2004; 279: 4221 - 4233.
Melanie Boerries, Mol. Cell. Biol., Jun 2007; 27: 4365 - 4373.
Patrick Most, J. Clin. Invest., Dec 2004; 114: 1550 - 1563.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ALAS2 (Source: Uniprot.org, NCBI)
Gene Name
ALAS2
Full Name
5-aminolevulinate synthase, erythroid-specific, mitochondrial
Weight
64.633kDa
Superfamily
class-II pyridoxal-phosphate-dependent aminotransferase family
Alternative Names
5-aminolevulinic acid synthase 2,5-aminolevulinate synthase, erythroid-specific, mitochondrial; ALASE; ALAS-E; aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); aminolevulinate, delta-, synthase 2; ANH1; ASBXLDPP; Delta-ALA synthase 2; delta-ALA synthetase; Delta-aminolevulinate synthase 2; EC 2.3.1.37; FLJ93603; XLSA ALAS2 ALAS-E, ALASE, ANH1, ASB, SIDBA1, XLDPP, XLEPP, XLSA 5-aminolevulinate synthase 2 5-aminolevulinate synthase, erythroid-specific, mitochondrial|5-aminolevulinic acid synthase 2|aminolevulinate, delta-, synthase 2|delta-ALA synthase 2|delta-ALA synthetase|delta-aminolevulinate synthase 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ALAS2, check out the ALAS2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ALAS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ALAS2 Antibody (A02525)
Hello CJ!
No publications found for A02525
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Customer Reviews
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