Anti-ALY ALYREF Antibody

Product Name

Anti-ALY ALYREF Antibody

View all Aly Antibodies

SKU/Catalog Number

A03580-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-ALY ALYREF Antibody catalog # A03580-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ALY ALYREF Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03580-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

1H1D2

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human ALY. at AA rangle: 90-170

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03580-1 is reactive to ALYREF in Human, Mouse, Rat

Applications

A03580-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

26.888kDa

Background of Aly

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Kelian Chen, et,al. (2003) J. Cell Sci ; 117: 4527 - 4536.
Vera Strasser, et,al. (2004) Mol. Cell. Biol ; 24: 1378 - 1386.
Izhar Ben-Shlomo, et,al. (2003) Sci. STKE ; 2003: 9.
H. M. Kim, et,al. (2002) PNAS ; 99: 4020.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of LOVO cells using ALY Polyclonal antibody.

Gene/Protein Information For ALYREF (Source: Uniprot.org, NCBI)

Alternative Names

Ally of AML-1 and LEF-1; ALY/REF; ALYBEFbZIP enhancing factor; bZIP-enhancing factor BEF; REF; THO complex 4; THO complex subunit 4; tho4; Transcriptional coactivator Aly/REF ALYREF ALY, ALY/REF, BEF, REF, THOC4 Aly/REF export factor THO complex subunit 4|THO complex 4|ally of AML-1 and LEF-1|bZIP enhancing factor|bZIP-enhancing factor BEF|tho4|transcriptional coactivator Aly/REF

For more info on ALYREF, check out the ALYREF Infographic

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In this infographic, you will see the following information for ALYREF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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