Anti-AMPK Beta 1 (1A7) monoclonal PRKAB1 Antibody

Product Name

Anti-AMPK Beta 1 (1A7) monoclonal PRKAB1 Antibody

View all AMPK beta 1 Antibodies

SKU/Catalog Number

M03741-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-AMPK Beta 1 (1A7) monoclonal PRKAB1 Antibody catalog # M03741-1. Tested in WB,ICC,IHC,IP applications. This antibody reacts with Human,Mouse,Rat,Monkey.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-AMPK Beta 1 (1A7) monoclonal PRKAB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03741-1)

Host

Mouse

Contents

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Monoclonal

Clone Number

4H6H6

Isotype

IgG

Immunogen

Purified recombinant fragment of p38beta (aa251-363) expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M03741-1 is reactive to PRKAB1 in Human, Monkey, Mouse, Rat

Applications

M03741-1 is guaranteed for IP, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

30.382kDa

Background of AMPK beta 1

Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000
IP: 1:50-200
ICC: 1:200
IHC: 1:800

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For PRKAB1 (Source: Uniprot.org, NCBI)

Alternative Names

5'-AMP-activated protein kinase beta-1 subunit; AMP-activated protein kinase beta subunit; AMPK beta -1 chain; AMPK beta 1; AMPK beta 1,5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPK; AMPKb; HAMPKb; MGC17785; PRKAB1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1 PRKAB1 AMPK, HAMPKb protein kinase AMP-activated non-catalytic subunit beta 1 5-AMP-activated protein kinase subunit beta-1|5-AMP-activated protein kinase beta-1 subunit|AMP-activated protein kinase beta subunit|AMPK beta -1 chain|AMPK beta 1|AMPK subunit beta-1|AMPKb|protein kinase, AMP-activated, beta 1 non-catalytic subunit|protein kinase, AMP-activated, noncatalytic, beta-1

For more info on PRKAB1, check out the PRKAB1 Infographic

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In this infographic, you will see the following information for PRKAB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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