Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody

Product Name

Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody

View all ANGPTL3 Antibodies

SKU/Catalog Number

A02929-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody (Catalog # A02929-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

ANGPTL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02929-1)

Host

Rabbit

Contents

ANGPTL3 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ANGPTL3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ANGPTL3. The immunogen is located within the last 50 amino acids of ANGPTL3.

Cross-reactivity

ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.

Reactive Species

A02929-1 is reactive to ANGPTL3 in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

53.6 kDa

Background of ANGPTL3

The angiopoietin-related protein 3 (ANGPTL3) is a member of a family of secreted proteins that function in angiogenesis (1). ANGPTL3 is processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis (2,3). Recent experiments have shown that a deficiency of ANGPTL3 is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, suggesting that ANGPTL3 may also play a role in modulating glucose metabolism (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02929-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ANGPTL3 antibody can be used for detection of ANGPTL3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information ANGPTL3

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