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Product Info Summary
| SKU: | A01167-1 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-AP-2 TFAP2A Antibody
SKU/Catalog Number
A01167-1
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-AP-2 TFAP2A Antibody (Catalog # A01167-1). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-AP-2 TFAP2A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01167-1)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human AP-2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01167-1 is reactive to TFAP2A in Human, Mouse, Rat
Applications
A01167-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
48.062kDa
Background of AP2 alpha
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602.
TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064.
Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768.
Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
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Western blot analysis of extracts from COLO205 cells, using AP-2 antibody A01167-1.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using AP-2 antibody A01167-1.
Protein Target Info & Infographic
Gene/Protein Information For TFAP2A (Source: Uniprot.org, NCBI)
Gene Name
TFAP2A
Full Name
Transcription factor AP-2-alpha
Weight
48.062kDa
Superfamily
AP-2 family
Alternative Names
Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2 transcription factor; AP2-alpha; AP2TFAP-2alpha; AP-2transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha); BOFS; FLJ51761; TFAP2; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2-alpha TFAP2A AP-2, AP-2alpha, AP2TF, BOFS, TFAP2 transcription factor AP-2 alpha transcription factor AP-2-alpha|AP-2 transcription factor|activating enhancer-binding protein 2-alpha|activator protein 2|transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TFAP2A, check out the TFAP2A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TFAP2A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AP-2 TFAP2A Antibody (A01167-1)
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No publications found for A01167-1
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Customer Reviews
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