Product Info Summary
SKU: | A06802 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-ARHGEF12/Larg Antibody
SKU/Catalog Number
A06802
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-ARHGEF12/Larg Antibody (Catalog # A06802). Tested in WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ARHGEF12/Larg Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06802)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human ARHGEF12.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06802 is reactive to ARHGEF12 in Human, Mouse
Applications
A06802 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
173.232kDa
Background of LARG
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Kourlas P.J., Proc. Natl. Acad. Sci. U.S.A. 97:2145-2150(2000).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Nagase T., DNA Res. 4:141-150(1997).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from RAW264.7 cells, using ARHGEF12 antibody A06802.
Protein Target Info & Infographic
Gene/Protein Information For ARHGEF12 (Source: Uniprot.org, NCBI)
Gene Name
ARHGEF12
Full Name
Rho guanine nucleotide exchange factor 12
Weight
173.232kDa
Alternative Names
ARHGC; ARHGEF12; DKFZp686O2372; KIAA0382PRO2792; LARG; LARGleukemia-associated rho guanine nucleotide exchange factor; Leukemia-associated RhoGEF; Rho guanine nucleotide exchange factor (GEF) 12; rho guanine nucleotide exchange factor 12 ARHGEF12 LARG, PRO2792 Rho guanine nucleotide exchange factor 12 rho guanine nucleotide exchange factor 12|Rho guanine nucleotide exchange factor (GEF) 12|leukemia-associated RhoGEF|leukemia-associated rho guanine nucleotide exchange factor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARHGEF12, check out the ARHGEF12 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ARHGEF12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ARHGEF12/Larg Antibody (A06802)
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No publications found for A06802
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