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Product Info Summary
| SKU: | A01609 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Arylsulfatase B ARSB Antibody
SKU/Catalog Number
A01609
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Arylsulfatase B ARSB Antibody (Catalog # A01609). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ARSB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Arylsulfatase B ARSB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01609)
Host
Rabbit
Contents
ARSB Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ARSB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ARSB. The immunogen is located within amino acids 460 - 510 of ARSB .
Cross-reactivity
ARSB antibody is human, mouse and rat reactive. At least two isoforms of ARSB are known to exist; this antibody only recognizes the longest isoform.
Reactive Species
A01609 is reactive to ARSB in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
59.7 kDa
Background of ARSB
Aryl sulfatase B (ARSB) forms a homodimer that hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate (1). ARSB localizes to the lysozyme as well as to the extracellular matrix (2). Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B (3), and can be treated with exogenous ARSB (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01609 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ARSB antibody can be used for detection of ARSB by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ARSB in mouse lung tissue lysate with ARSB antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of ARSB in human lung tissue with ARSB antibody at 2.5 μg/mL.
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Immunofluorescence of ARSB in human lung tissue with ARSB antibody at 20 μg/mL.
Specific Publications For Anti-Arylsulfatase B ARSB Antibody (A01609)
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