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Product Info Summary
| SKU: | A02773 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-B-cell lymphoma 3 protein BCL3 Antibody
SKU/Catalog Number
A02773
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-B-cell lymphoma 3 protein BCL3 Antibody (Catalog # A02773). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
BCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-B-cell lymphoma 3 protein BCL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02773)
Host
Rabbit
Contents
BCL3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3. The immunogen is located within amino acids 360 - 410 of BCL3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IZUMO1 antibody is human specific. At least four isoforms of IZUMO1 are known to exist; this antibody will detect the two longest isoforms.
Reactive Species
A02773 is reactive to BCL3 in Human
Applications
A02773 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
47.584kDa
Background of BCL3
The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ-B proteins. The expression of this gene can be induced by NF-κ-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For BCL3 (Source: Uniprot.org, NCBI)
Gene Name
BCL3
Full Name
B-cell lymphoma 3 protein
Weight
47.584kDa
Alternative Names
B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3-encoded protein; BCL-3; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3 BCL3 BCL4, D19S37 BCL3 transcription coactivator B-cell lymphoma 3 protein|B cell CLL/lymphoma 3|B-cell leukemia/lymphoma 3|B-cell lymphoma 3-encoded protein|BCL-3|chronic lymphatic leukemia protein|proto-oncogene BCL3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BCL3, check out the BCL3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BCL3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-B-cell lymphoma 3 protein BCL3 Antibody (A02773)
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No publications found for A02773
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