Product Info Summary
SKU: | PA2155 |
---|---|
Size: | 100 μg/vial |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-beta Arrestin 1/ARRB1 Antibody
View all beta-Arrestin 1 Antibodies
SKU/Catalog Number
PA2155
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-beta Arrestin 1/ARRB1 Antibody catalog # PA2155. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-beta Arrestin 1/ARRB1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2155)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human beta Arrestin 1, identical to the related rat and mouse sequences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2155 is reactive to ARRB1 in Human, Mouse, Rat
Applications
PA2155 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
18 kDa
Calculated molecular weight
47.066kDa
Background of beta-Arrestin 1
Arrestin, beta 1, also known as ARRB1, is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization, this gene is mapped to 11q13.4. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Validation Images & Assay Conditions
Click image to see more details
Anti-beta Arrestin 1 antibody, PA2155, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Click image to see more details
Anti-beta Arrestin 1 antibody, PA2155, Western blotting
Lane 1: Rat Lung Tissue Lysate
Lane 2: Rat Skeletal Muscle Tissue Lysate
Lane 3: SW620 Cell Lysate
Protein Target Info & Infographic
Gene/Protein Information For ARRB1 (Source: Uniprot.org, NCBI)
Gene Name
ARRB1
Full Name
Beta-arrestin-1
Weight
47.066kDa
Superfamily
arrestin family
Alternative Names
ARB1; ARR1; ARRB1; arrestin 2; Arrestin beta-1; arrestin, beta 1; betaArrestin 1; beta-Arrestin 1; beta-arrestin-1 ARRB1 ARB1, ARR1 arrestin beta 1 beta-arrestin-1|arrestin 2|non-visual arrestin-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARRB1, check out the ARRB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ARRB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-beta Arrestin 1/ARRB1 Antibody (PA2155)
Hello CJ!
No publications found for PA2155
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-beta Arrestin 1/ARRB1 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-beta Arrestin 1/ARRB1 Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
6 Customer Q&As for Anti-beta Arrestin 1/ARRB1 Antibody
Question
Will anti-beta Arrestin 1/ARRB1 antibody PA2155 work on monkey IHC with peripheral blood?
Verified Customer
Verified customer
Asked: 2020-02-10
Answer
Our lab technicians have not tested anti-beta Arrestin 1/ARRB1 antibody PA2155 on monkey. You can run a BLAST between monkey and the immunogen sequence of anti-beta Arrestin 1/ARRB1 antibody PA2155 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated monkey samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in monkey peripheral blood in IHC, you can get your next antibody for free.
Boster Scientific Support
Answered: 2020-02-10
Question
Thanks for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for cervix carcinoma using anti-beta Arrestin 1/ARRB1 antibody PA2155. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2020-01-15
Answer
I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-01-15
Question
I was wanting to use your anti-beta Arrestin 1/ARRB1 antibody for WB for rat cervix carcinoma on frozen tissues, but I want to know if it has been validated for this particular application. Has this antibody been validated and is this antibody a good choice for rat cervix carcinoma identification?
Verified Customer
Verified customer
Asked: 2019-09-26
Answer
As indicated on the product datasheet, PA2155 anti-beta Arrestin 1/ARRB1 antibody has been tested for IHC, WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in rat cervix carcinoma in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-09-26
Question
Please see the WB image, lot number and protocol we used for cervix carcinoma using anti-beta Arrestin 1/ARRB1 antibody PA2155. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2019-07-29
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-07-29
Question
We are currently using anti-beta Arrestin 1/ARRB1 antibody PA2155 for mouse tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on monkey tissues as well?
Verified Customer
Verified customer
Asked: 2017-09-27
Answer
The anti-beta Arrestin 1/ARRB1 antibody (PA2155) has not been validated for cross reactivity specifically with monkey tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2017-09-27
Question
Do you have a BSA free version of anti-beta Arrestin 1/ARRB1 antibody PA2155 available?
Z. Krishna
Verified customer
Asked: 2014-12-15
Answer
I appreciate your recent telephone inquiry. I can confirm that some lots of this anti-beta Arrestin 1/ARRB1 antibody PA2155 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2014-12-15