Anti-CACNA1H Antibody

Product Name

Anti-CACNA1H Antibody

View all Cav3.2 Antibodies

SKU/Catalog Number

A01406-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CACNA1H Antibody (Catalog # A01406-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

CACNA1H antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-CACNA1H Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01406-1)

Host

Rabbit

Contents

CACNA1H antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

CACNA1H antibody was raised against a 16 amino acid peptide near the center of human CACNA1H. The immunogen is located within amino acids 1010 - 1060 of CACNA1H.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

CACNA1H antibody is human, mouse and rat reactive. Multiple isoforms of CACNA1H are known to exist.

Reactive Species

A01406-1 is reactive to CACNA1H in Human, Mouse, Rat

Applications

A01406-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

259.163kDa

Background of Cav3.2

The calcium channel protein CACNA1H is a T-type member of the alpha-1 subunit family that is part of the voltage-dependent calcium channel complex which mediates the influx of calcium ions into the cell upon membrane polarization (1,2). CACNA1H is a subunit of Cav3.2 T-type calcium channel that is involved in neurological disorders such as epilepsy and pain (2,3). CACNA1H associates with the caveolin protein Cav-3 and it is thought that Cav-3 regulates the Protein Kinase A (PKA) modulation of CACNA1H-containing Cav3.2 T-type calcium channels (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CACNA1H antibody can be used for detection of CACNA1H by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of CACNA1H in 293 cell lysate with CACNA1H antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.

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Immunohistochemistry of CACNA1H in mouse brain tissue with CACNA1H antibody at 5 μg/ml.

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Immunofluorescence of CACNA1H in mouse brain tissue with CACNA1H antibody at 20 μg/ml.

Gene/Protein Information For CACNA1H (Source: Uniprot.org, NCBI)

Alternative Names

CACNA1HB; calcium channel, voltage-dependent, T type, alpha 1H subunit; calcium channel, voltage-dependent, T type, alpha 1Hb subunit; Cav3.2; ECA6; EIG6; FLJ90484; Low-voltage-activated calcium channel alpha1 3.2 subunit; low-voltage-activated calcium channel alpha13.2 subunit; voltage dependent t-type calcium channel alpha-1H subunit; voltage-dependent T-type calcium channel subunit alpha-1H; voltage-gated calcium channel alpha subunit Cav3.2; voltage-gated calcium channel alpha subunit CavT.2; Voltage-gated calcium channel subunit alpha Cav3.2 CACNA1H CACNA1HB, Cav3.2, ECA6, EIG6, HALD4 calcium voltage-gated channel subunit alpha1 H voltage-dependent T-type calcium channel subunit alpha-1H|calcium channel, voltage-dependent, T type, alpha 1H subunit|calcium channel, voltage-dependent, T type, alpha 1Hb subunit|low-voltage-activated calcium channel alpha1 3.2 subunit|low-voltage-activated calcium channel alpha13.2 subunit|voltage dependent t-type calcium channel alpha-1H subunit|voltage-gated calcium channel alpha subunit Cav3.2|voltage-gated calcium channel alpha subunit CavT.2|voltage-gated calcium channel subunit alpha Cav3.2

For more info on CACNA1H, check out the CACNA1H Infographic

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In this infographic, you will see the following information for CACNA1H: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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