Anti-CARMA1 CARD11 Antibody

CARD11/CARMA1 antibody

Boster Bio Anti-CARMA1 CARD11 Antibody (Catalog # A00740). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A00740
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

Product Name

Anti-CARMA1 CARD11 Antibody

View all CARD11/CARMA1 Antibodies

SKU/Catalog Number

A00740

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CARMA1 CARD11 Antibody (Catalog # A00740). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

CARMA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-CARMA1 CARD11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00740)

Host

Rabbit

Contents

CARMA1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

CARMA1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1. The immunogen is located within the last 50 amino acids of CARMA1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00740 is reactive to CARD11 in Human, Mouse

Applications

A00740 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Background of CARD11/CARMA1

CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the IκK complex, thereby regulating activation of the NF-κB transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

CARMA1 antibody can be used for detection of CARMA1 by Western blot at 0.5 to 2 μg/mL. A band at approximately 125 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Validation Images & Assay Conditions

Gene/Protein Information For CARD11 (Source: Uniprot.org, NCBI)

Uniprot ID

Q9BXL7

Gene ID

84433

Gene Name

CARD11

Full Name

Caspase recruitment domain-containing protein 11

Weight

133.284kDa

Alternative Names

BIMP3; BIMP3card-maguk protein 1; CARD11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; CARMA1bcl10-interacting maguk protein 3; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; MGC133069 CARD11 BENTA, BIMP3, CARMA1, IMD11, IMD11A, PPBL caspase recruitment domain family member 11 caspase recruitment domain-containing protein 11|CARD-containing MAGUK protein 1|bcl10-interacting maguk protein 3|carma 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CARD11, check out the CARD11 Infographic

CARD11 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CARD11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Size

Total: $404

SKU:A00740

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Ships directly to USA and Canada. For other regions, visit our distributors page

Bulk Inquiry

In stock
Order Product
A00740
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$404.00

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