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CASP1 antibody (M00048) performs well in IHC, WB and shows reactivity with Human, Rat.

Validated for inter-lot consistency, specificity, and reproducibility
Committed to quality since 1993
Over 23 Publications

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Immunohistochemical analysis of paraffin-embedded human liver, using Caspase-1 Antibody.

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Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

CASP1 antibody

23 Publications

Reactive Species	Host	Application
Human, Rat	Rabbit	IHC, WB

Tested Applications

CASP1 antibody was positively detected by WB in:

human THP-1 whole cell, human SIHA whole cell, human A431 whole cell, human RT4 whole cell

Suggested blocking solution with 5% non-fat milk or BSA; (*)Recommended protein loading: 20-40 ug per lane

CASP1 antibody was positively detected by IHC in:

human liver tissue

Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.

Reactive Data

Boster Guarantee: All Tested Recommend Predicted species What is this?

IHC

Human

Tested

Recommend

Product Information

Product Name

Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody
View all CASP1 Antibodies

Form

Liquid

Uniprot

P29466

Gene ID

834

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Host

Rabbit

Contents

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Monoclonal

Clone Number

DCB-3

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human Caspase-1

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Observed Molecular Weight

35-48 kDa

Calculated Molecular Weight

45.2 kDa

Cite This Product

Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00048)

Protocols

Western Blot protocol for CASP1 antibody

Review Protocol

Immunohistochemistry (IHC) protocol for CASP1 antibody

Review Protocol

Publications

Repurposing Lamivudine: A novel therapeutic strategy for ischemic stroke targeting the glycolytic enzyme Pgk1

Published: 2025-11-08

Journal: BIOCHEMICAL PHARMACOLOGY

Application: WB

Impact Factor: 5.60

Species: Rat

PMID: 41213407

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Free Secondary Antibody

Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

CASP1 antibody

Overview

Tested Applications

Recommend Dilution

Reactive Data

Product Information

Protocols

Publications

Repurposing Lamivudine: A novel therapeutic strategy for ischemic stroke targeting the glycolytic enzyme Pgk1

Berberine attenuates the expression of NLRP3 and downstream inflammasome effectors in diabetic retinopathy

Lipoic acid-modified epirubicin liposomal system for tumor-targeted drug delivery and cardiotoxicity reduction

Olfactory ensheathing cells transplantation alleviates cancer pain by inhibiting P2X7 receptor expression mediated activation of microglia

Protocatechuic acid mitigates 5-fluorouracil-triggered renal and hepatic injury in rats

GBP1 promotes acute rejection after liver transplantation by inducing Kupffer cells pyroptosis

Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain

Saroglitazar ameliorates 5- Fluorouracil-induced hepatorenal damage in rats

Stress-induced NLRP3 inflammasome activation and myelin alterations in the hippocampus of PTSD rats

Effects of Rutaecarpine on Chronic Atrophic Gastritis Through Nucleotide-binding Oligomerization Domain-like Receptors and Inflammasomes

Hsa_circ_0008833 promotes COPD progression via inducing pyroptosis in bronchial epithelial cells

A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury

Involvement of the heat shock response (HSR) regulatory pathway in cadmium-elicited cerebral damage

Edaravone dexborneol alleviates cerebral ischemia-reperfusion injury through NF-κB/NLRP3 signal pathway

Short-Chain Fatty Acids Weaken Ox-LDL-Induced Cell Inflammatory Injury by Inhibiting the NLRP3/Caspase-1 Pathway and Affecting Cellular Metabolism in THP-1 Cells

lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR‑223‑3p/NLRP3 axis

Terazosin Stimulates Pgk1 to Remedy Gastrointestinal Disorders

Azeliragon ameliorates Alzheimer's disease via the Janus tyrosine kinase and signal transducer and activator of transcription signaling pathway

Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission

Programmed death-ligand 1 triggers PASMCs pyroptosis and pulmonary vascular fibrosis in pulmonary hypertension

Pre-administration of luteoline attenuates neonatal sevoflurane-induced neurotoxicity in mice

Vector Analysis of Cytoskeletal Structural Tension and the Mechanisms that Underpin Spectrin-Related Forces in Pyroptosis

Role of NLRP3 Inflammasome in Eosinophilic and Non-eosinophilic Chronic Rhinosinusitis with Nasal Polyps

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