Anti-CCRL2/Cram A Antibody

Product Name

Anti-CCRL2/Cram A Antibody

View all CCRL2 Antibodies

SKU/Catalog Number

A09152

Size

100μl

Form

Liquid

Description

Boster Bio Anti-CCRL2/Cram A Antibody catalog # A09152. Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CCRL2/Cram A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09152)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

3D5B1

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CCRL2 at amino acid range 141-190

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A09152 is reactive to CCRL2 in Human

Applications

A09152 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

39.513kDa

Background of CCRL2

APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using CCRL2 Polyclonal antibody.

Gene/Protein Information For CCRL2 (Source: Uniprot.org, NCBI)

Alternative Names

CCRL2/LCCR; LCCR CCRL2 ACKR5, CKRX, CRAM, CRAM-A, CRAM-B, HCR C-C motif chemokine receptor like 2 C-C chemokine receptor-like 2|atypical chemokine receptor 5|chemokine (C-C motif) receptor-like 2|chemokine receptor CCR11|chemokine receptor X|putative MCP-1 chemokine receptor

For more info on CCRL2, check out the CCRL2 Infographic

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In this infographic, you will see the following information for CCRL2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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