Product Info Summary
SKU: | A03248 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC |
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Product info
Product Name
Anti-CD109 antigen CD109 Antibody
SKU/Catalog Number
A03248
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CD109 antigen CD109 Antibody catalog # A03248. Tested in ELISA, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CD109 antigen CD109 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03248)
Host
Rabbit
Contents
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide from human CD109 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03248 is reactive to CD109 in Human
Applications
A03248 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
161.689kDa
Background of CD109
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.
Inoue S., Proc. Natl. Acad. Sci. U.S.A. 90:11117-11121(1993).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Rush J., Nat. Biotechnol. 23:94-101(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-P 1:50-300
ELISA 1:5000-20000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of CD109 using Anti-CD109 antigen CD109 Antibody (A03248).
Immunohistochemical analysis of paraffin-embedded human-liverProtein Target Info & Infographic
Gene/Protein Information For CD109 (Source: Uniprot.org, NCBI)
Gene Name
CD109
Full Name
CD109 antigen
Weight
161.689kDa
Superfamily
protease inhibitor I39 (alpha-2-macroglobulin) family
Alternative Names
150 kDa TGF-beta-1-binding protein; activated T-cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109 antigen (Gov platelet alloantigens); CD109 antigen; CD109 molecule; CD109; CPAMD7; CPAMD7r150; DKFZp762L1111; FLJ38569; FLJ41966; Gov platelet alloantigens; p180; Platelet-specific Gov antigen; RP11-525G3.1 CD109 CPAMD7, p180, r150 CD109 molecule CD109 antigen|150 kDa TGF-beta-1-binding protein|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7|Gov platelet alloantigens|activated T-cell marker CD109|platelet-specific Gov antigen
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD109, check out the CD109 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD109: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CD109 antigen CD109 Antibody (A03248)
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No publications found for A03248
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