Anti-CD81 antigen CD81 Antibody

Product Name

Anti-CD81 antigen CD81 Antibody

View all CD81 Antibodies

SKU/Catalog Number

A01281

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CD81 antigen CD81 Antibody (Catalog # A01281). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

CD81 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-CD81 antigen CD81 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01281)

Host

Rabbit

Contents

CD81 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

CD81 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human CD81. The immunogen is located within amino acids 30 - 80 of CD81.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Biotin-Beta-Actin antibody is human, mouse, rat, rabbit, chicken, and drosophila reactive.

Reactive Species

A01281 is reactive to CD81 in Human, Mouse, Rat

Applications

A01281 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

25.809kDa

Background of CD81

CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CD81 antibody can be used for detection of CD81 by Western blot at 2.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of CD81 in human lung tissue lysate with CD81 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking petide.

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Immunohistochemistry of CD81 in human lung tissue with CD81 antibody at 5 μg/mL.

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Immunofluorescence of CD81 in A549 cells with CD81 antibody at 20 μg/mL.

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Immunohistochemistry of CD81 in human brain tissue with CD81 antibody at 2 μg/ml.

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Immunofluorescence of CD81 in human brain tissue with CD81 antibody at 10 μg/ml.

Green: CD81 Antibody (A01281)
Blue: DAPI staining

Gene/Protein Information For CD81 (Source: Uniprot.org, NCBI)

Alternative Names

CD81 antigen (target of antiproliferative 1); CD81 antigen; CD81 molecule; CD81; CVID6; TAPA1; TAPA-1; Target of the antiproliferative 1; Tetraspanin-28; TSPAN28; Tspan-28; tspan-28,26 kDa cell surface protein TAPA-1; TSPAN28S5.7 CD81 CVID6, S5.7, TAPA1, TSPAN28 CD81 molecule CD81 antigen|26 kDa cell surface protein TAPA-1|CD81 antigen (target of antiproliferative antibody 1)|tetraspanin-28|tspan-28

For more info on CD81, check out the CD81 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CD81: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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