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- Table of Contents
CDK4 antibody (M00159-2) performs well in IHC-P, WB and shows reactivity with Human, Mouse.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunohistochemical analysis of paraffin-embedded Human Breast cancer section using Pink1. M00159-2 was diluted at 1:300 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
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Anti-CDK4 Antibody
CDK4 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse | Mouse | IHC-P, WB |
Recommend Dilution
Application
Dilution
Species
IHC: 1:300
WB: 1:2000
IHC-P: 1:25
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-CDK4 Antibody
View all CDK4 Antibodies
View all CDK4 Antibodies
Uniprot
Gene ID
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1529CT850.162.73
Isotype
IgG2a,κ
Immunogen
This CDK4 antibody is generated from a mouse immunized with a recombinant protein.
Calculated Molecular Weight
33.7 kDa
Background of CDK4
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Cite This Product
Anti-CDK4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00159-2)
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Product Promise
We promise Anti-CDK4 Antibody performs excellently in relevant applications for IHC-P, WB. If it doesn't perform as promised, we will refund the product. Learn more
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M00159-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00
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We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 5, 2026