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Product Info Summary
| SKU: | A00511 |
|---|---|
| Size: | 100uL |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody
SKU/Catalog Number
A00511
Size
100uL
Form
Liquid (sterile filtered)
Description
Boster Bio Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody (Catalog # A00511). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Cite This Product
Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00511)
Host
Rabbit
Contents
0.01% (w/v) Sodium Azide
Clonality
Polyclonal
Isotype
Antiserum
Immunogen
CDK5 (p31) peptide corresponding to the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00511 is reactive to CDK5 in Human, Mouse, Rat
Applications
A00511 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
33.304kDa
Background of CDK5
The protein encoded by the gene CDK5 is involved in the control of the cell cycle and interacts with D1 and D3-type G1 cyclins. CDK5 belongs to the protein kinase superfamily, the CMGC Ser/Thr protein kinase family and the CDC2/CDKX subfamily. CDK5 phosphorylates histone H1, tau, MAP2 and NF-H and NF-M and also interacts with p35 which activates the kinase. CDK5 forms a heterodimer, where CDK5 is the catalytic subunit and p35 is the regulatory subunit. CDK5 is also found in a trimolecular complex with CABLES1 and ABL1. CDK5 is a cytoplasmic protein.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELISA: 1:5,000 - 1:20,000
IHC: 1:500
IP: 1:100
WB: 1:500 - 1:5,000
Validation Images & Assay Conditions
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Cdk5 was detected in paraffin-embedded sections of human brain cortex tissues using rabbit anti-Cdk5 Antigen Affinity purified polyclonal antibody (Catalog # A00511) at 1:500. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
Protein Target Info & Infographic
Gene/Protein Information For CDK5 (Source: Uniprot.org, NCBI)
Gene Name
CDK5
Full Name
Cyclin-dependent-like kinase 5
Weight
33.304kDa
Superfamily
protein kinase superfamily
Alternative Names
CDK5; CDKN5; Cell division protein kinase 5; cyclin-dependent kinase 5; EC 2.7.11; EC 2.7.11.22; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit CDK5 LIS7, PSSALRE cyclin dependent kinase 5 cyclin-dependent-like kinase 5|TPKII catalytic subunit|cell division protein kinase 5|epididymis secretory sperm binding protein|protein kinase CDK5 splicing|serine/threonine-protein kinase PSSALRE|tau protein kinase II catalytic subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CDK5, check out the CDK5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CDK5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody (A00511)
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No publications found for A00511
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Recommended Resources
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Customer Reviews
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Customer Q&As
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