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Product Info Summary
| SKU: | A01346 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC |
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Product info
Product Name
Anti-CHD8 Antibody
SKU/Catalog Number
A01346
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CHD8 Antibody catalog # A01346. Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CHD8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01346)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Cdc25C around the phosphorylation site of T48.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01346 is reactive to CHD8 in Human
Applications
A01346 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
290.519kDa
Background of CHD8
The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). NCOA3 is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. NCOA3 may be associated with diseases such as breast cancer and meningothelial meningioma. Anti-NCOA3 Antibody is useful for researchers interested in cancer research, chromatin binding, transcription coactivator activity, Immunology, and Nuclear Signaling research.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-p 1:50-300
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For CHD8 (Source: Uniprot.org, NCBI)
Gene Name
CHD8
Full Name
Chromodomain-helicase-DNA-binding protein 8
Weight
290.519kDa
Superfamily
SNF2/RAD54 helicase family
Alternative Names
ATP-dependent helicase CHD8; CHD-8; chromodomain helicase DNA binding protein 8; DKFZp686N17164; duplin; EC 3.6.1; EC 3.6.1.7; EC 3.6.4.12; Helicase with SNF2 domain 1chromodomain-helicase-DNA-binding protein 8; HELSNF1; KIAA1564axis duplication inhibitor CHD8 AUTS18, HELSNF1 chromodomain helicase DNA binding protein 8 chromodomain-helicase-DNA-binding protein 8|ATP-dependent helicase CHD8|axis duplication inhibitor|duplin|helicase with SNF2 domain 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CHD8, check out the CHD8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CHD8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CHD8 Antibody (A01346)
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No publications found for A01346
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Customer Reviews
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