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Product Info Summary
| SKU: | M03452 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-CK-MM Monoclonal Antibody
View all Creatine Kinase, Muscle/CKMM Antibodies
SKU/Catalog Number
M03452
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CK-MM Monoclonal Antibody catalog # M03452. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CK-MM Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03452)
Host
Mouse
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Monoclonal
Clone Number
6A12-C8
Isotype
IgG
Immunogen
Purified recombinant human CK-MM protein expressed in E.coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
M03452 is reactive to CKM in Human
Applications
M03452 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
43.101kDa
Background of Creatine Kinase, Muscle/CKMM
Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000
ELISA 1:10000-20000
Validation Images & Assay Conditions
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Figure 1. ELISA validation of CKM using Anti-CK-MM Monoclonal Antibody (M03452).
Indirect ELISA assay for anti-CK-MM mouse mAb. CKBB as control antigen. Antigen coating concentration:4ug/ml.Protein Target Info & Infographic
Gene/Protein Information For CKM (Source: Uniprot.org, NCBI)
Gene Name
CKM
Full Name
Creatine kinase M-type
Weight
43.101kDa
Superfamily
ATP:guanido phosphotransferase family
Alternative Names
CKM; CKMM; CKMMcreatine kinase M-type; Creatine kinase M chain; Creatine Kinase MM; creatine kinase, muscle; creatine kinase-M; EC 2.7.3; EC 2.7.3.2; M-CK CKM CKMM, CPK-M, M-CK creatine kinase, M-type creatine kinase M-type|creatine kinase M chain|creatine kinase, muscle|creatine phosphokinase M-type
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CKM, check out the CKM Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CKM: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CK-MM Monoclonal Antibody (M03452)
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No publications found for M03452
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Customer Reviews
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