Product Info Summary
SKU: | A01896 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, IHC |
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Product info
Product Name
Anti-CKR-1 CCR1 Antibody
SKU/Catalog Number
A01896
Size
100ul
Form
Liquid
Description
Boster Bio Anti-CKR-1 CCR1 Antibody catalog # A01896. Tested in ELISA, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CKR-1 CCR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01896)
Host
Rabbit
Contents
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide from human CKR-1 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01896 is reactive to CCR1 in Human
Applications
A01896 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
41.173kDa
Background of CCR1
Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
McKay M.J., Genomics 36:305-315(1996).
Sadano H., Biochem. Biophys. Res. Commun. 267:418-422(2000).
Nomura N., DNA Res. 1:223-229(1994).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC-P 1:50-300
ELISA 1:5000-20000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunohistochemistry validation of CCR1 using Anti-CKR-1 CCR1 Antibody (A01896).
Immunohistochemical analysis of paraffin-embedded human-small-intestineClick image to see more details
Figure 2. Immunohistochemistry validation of CCR1 using Anti-CKR-1 CCR1 Antibody (A01896).
Immunohistochemical analysis of paraffin-embedded human-spleenProtein Target Info & Infographic
Gene/Protein Information For CCR1 (Source: Uniprot.org, NCBI)
Gene Name
CCR1
Full Name
C-C chemokine receptor type 1
Weight
41.173kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
C-C chemokine receptor type 1; CC-CKR-1; CCR1; CCR-1; CD191 antigen; CD191; chemokine (C-C motif) receptor 1; CKR1; CKR-1; CMKBR1SCYAR1; CMKR1; HM145C-C CKR-1; LD78 receptor; Macrophage inflammatory protein 1-alpha receptor; MIP-1alpha-R; MIP1aR; RANTES receptor; RANTES-R CCR1 CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 C-C motif chemokine receptor 1 C-C chemokine receptor type 1|C-C CKR-1|CC-CKR-1|CCR-1|LD78 receptor|MIP-1alpha-R|RANTES receptor|RANTES-R|chemokine (C-C motif) receptor 1|macrophage inflammatory protein 1-alpha receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CCR1, check out the CCR1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CCR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CKR-1 CCR1 Antibody (A01896)
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No publications found for A01896
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Customer Reviews
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